Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 476-280-7 | CAS number: 109113-72-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006-11-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- 2004
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- 1992
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- issued 2006-12-21
- Type of method:
- HPLC method
- Remarks:
- with UV detector at 210 nm
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- Pow
- Partition coefficient:
- 79
- Temp.:
- 25 °C
- pH:
- 2.4
- Remarks on result:
- other: Pow =79+/- 0.2 (95% confidence interval).
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.9
- Temp.:
- 25 °C
- pH:
- 2.4
- Remarks on result:
- other: 1.90 + 0.001 (95% confidence interval).
- Conclusions:
- The Partition coefficient (Pow) was determined using HPLC to be 79 +/- 0.2 (95 % confidence interval). The Log Pow is 1.90 +/- 0.001 (95% confidence interval).
Reference
Chemical name |
Retention time [min] |
Log k |
Log Pow |
Pow |
Repeatability ¿ Log Pow Log unit |
Calculated data |
|||||
CD 605 |
7.88 |
0.261 |
1.90 |
79 |
0.002 |
7.88 |
0.261 |
1.90 |
79 |
||
7.88 |
0.261 |
1.90 |
79 |
||
7.88 |
0.261 |
1.90 |
79 |
||
7.87 |
0.260 |
1.90 |
79 |
||
7.87 |
0.260 |
1.90 |
79 |
||
Mean |
7.88 |
0.261 |
1.90 |
79 |
|
Conf. (95%) |
- |
- |
0.001 |
0.2 |
|
CV% |
0.1 |
- |
- |
- |
|
Description of key information
Log Pow = 1.90 +/- 0.001 at 25 °C (95% confidence interval),
OECD Test Guideline 117 (2004) and EC Method A.8 (1992), (by HPLC method)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.9
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
