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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 207-988-4 | CAS number: 504-29-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Guidance on Safe Use
Administrative data
First-aid measures
Eyes: If in eyes rinse cautiously with water for at least 15 minutes. Remove contact lenses if easy to do so. Continue rinsing. Seek immediate medical
attention.
Skin: Immediately take off all contaminated clothing. Wash thoroughly with water for at least 15 minutes. Seek medical attention.
Inhalation: Remove to fresh air and keep at rest in a position comfortable for breathing. Monitor for respiratory distress. Apply artificial respiration ifnot breathing. Do not use mouth-to-mouth methods if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket
mask equipped with a one-way valve or other proper respiratory medical device.
Ingestion: If swallowed rinse mouth. Do NOT induce vomiting by use of emetics. Seek medical attention, call a poison center if you feel unwell.
Fire-fighting measures
Fire Fighting Procedures:
Extinguishant: Carbon dioxide, dry chemical, alcohol foam
If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with
difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources.
Accidental release measures
Exposure Control and emergency control :
Wear protective clothing, full boots, impervious gloves, safety glasses and Self Contained Breathing Apparatus. Alert Emergency Responders and tell them location and nature of hazard. Shut off all possible sources of ignition and increase ventilation. Avoid breathing vapors and contact with skin
and eyes.
Environmental precautions:
Clean up all spills immediately and prevent, by spillage from entering drains or water and watercourses. Inform authorities in event of contamination of any public sewers, drains or water bodies.
Clean up methods:
Collect recoverable product into labeled containers for recycling, recovery or disposal. Spread area with lime or absorbent material, and leave for at
least 1 hour before washing.
Handling and storage
In general materials which are toxic as stored or which can decompose into toxic components should be stored in cool, well- ventilated place out of sun, away from areas of high fire hazard and should be periodically inspected & monitored. Incompatible materials should be isolated.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 2671
Shipping information
- Proper shipping name and description:
- Aminopyridines (o-;m-;p-;)
- Chemical name:
- 2-Aminopyridine
- Language:
- English
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 2671
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 2671
Shipping information
- Proper shipping name and description:
- Aminopyridines (o-;m-;p-;)
- Chemical name:
- 2-Aminopyridine
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 2671
Shipping information
- Proper shipping name and description:
- Aminopyridines (o, m, p)
- Chemical name:
- 2-Aminopyridine
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
WEL 8hr TWA : 0.5 (ppm)
STEL: 2.0 ppm
NIOSH: 0.5 ppm TWA, 2 mg/m3 TWA 5 ppm IDLH
ACGIH: 0.5 ppm TWA
OSHA - Final PELs: 0.5 ppm TWA; 2 mg/m3 TWA
Engineering Controls
Provide exhaust ventilation or other engineering controls to keep the relevant airborne concentrations below their respective occupational exposure limits. Local ventilation is usually preferred. Ensure that eyewash stations and safety showers are close to the workstation location.
Personal Protection
Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances
handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier.
Hands: Wear appropriate protective gloves to prevent skin exposure or as described below.
In full contact:
Glove Material: nitrile rubber
Layer Thickness: 0.11 mm
Breakthrough time: > 480 Min
In splash contact:
Glove Material: nitrile rubber
Layer Thickness: 0.11 mm
Breakthrough time: > 480 Min
Eyes: Safety goggles/ Chemical Safety glasses and Face shield.
Clothing: Boots and clothing to prevent contact.
Respirator: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European
Standard EN 149 approved respirator when necessary.
Stability and reactivity
Reactivity
2-Aminopyridine is white leaflets or large colorless crystals like odor Characteristic- similar to pyridine. It is Soluble in water, alcohol, benzene, ether, hot petrol ether, acetone and organic solvents; slightly soluble in chloroform.
Chemical stability
Oxidizes and darkens with time. Heat and light accelerate this process.
Hazardous Polymerization will not occur.
Conditions to avoid
Keep away from heat, sparks, flame, high temperature and incompatible chemicals.
Incompatible materials
Strong oxidizing agents.
Hazardous decomposition products
Thermal decomposition may produce carbon monoxide and oxides of nitrogen, carbon dioxide & nitrogen and irritating and toxic fumes.
Disposal considerations
Dispose of this material in accordance with standard practice for disposal of potentially hazardous materials as required by applicable federal, state or local laws. Note that disposal regulations may also apply to empty containers and equipment rinsates.
2-Aminopyridine may be disposed of: 1. By making packages of 2-aminopyridine in paper or other flammable material and burning in a suitable
combustion chamber equipped with an appropriate effluent gas cleaning device.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.