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EC number: 603-333-5 | CAS number: 129423-55-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 Jan 2020 to 31 Jan 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Juvenile Daphnia magna (Straus), less than 24 hours old, were taken from healthy parental laboratory cultures, held and maintained at the test facility. These cultures were set up originally from dormant eggs (ephippia) supplied by MicroBioTests Inc., Belgium.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Test temperature:
- See table 1
- pH:
- See table 1
- Dissolved oxygen:
- See table 1
- Details on test conditions:
- Due to the low solubility of the test substance it was expected that there would not be a toxic effect at the limit of solubility therefore a definitive limit test was conducted at a nominal loading rate of 100 mg/L. A control group was also included.
The test vessels were 100 mL tall form glass beakers (filled to approximately 50 mL). Four replicate test vessels were prepared for the control and test concentration.
At the start of the test, 50.00 mg of test substance was weighed onto a glass weigh boat, this was then suspended below the water level of the Elendt M4 media fully submerging the test substance. Preparations were then allowed to stir slowly (such that a slight dimple no deeper than 1 cm was formed at the surface) for ca 48 hours, followed by a ca 1 hour settle period. Final media were then syphoned from the mid-section of the vessel or aqueous phase. The control was treated in the same manner without the addition of test substance.
Five juvenile Daphnia magna, less than 24 hours old, were added to each test and control vessel, using a wide bore glass pipette to avoid damaging the animals during transfer. The Daphnia magna were not fed during the test.
After 24 and 48 hours, the Daphnia magna in each test vessel were observed for evidence of immobility.
The observations differentiated between mobile and immobile daphnids. An individual was considered immobile if, when the contents of the test vessel were briefly agitated, it did not swim during a 15-second period of observation. In addition, Daphnia magna submerged in the body of the test media and those that were held at the surface of the test media were also recorded.
The test was conducted with a 16-hour light: 8-hour dark photoperiod.
The pH, dissolved oxygen concentration (% air saturation value (ASV) and mg/L) and temperatures were determined in freshly prepared test media at the start of the test and in the old media at 48 hours. Continuous temperatures were measured using a digital (min/max) thermometer in an additional vessel maintained in the test area.
The freshly prepared media water quality measurements were performed on media sampled directly from preparation flasks. The old media water quality measurements were conducted using pooled replicate samples of old test media. - Reference substance (positive control):
- yes
- Remarks:
- Potassium Dichromate with 100% purity used as a test substance, experimental dates 10th December 2019-12 December 2019.
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- The 48-hour acute toxicity of Dioctyldodecyl Dodecanedioate to the freshwater planktonic crustacean, Daphnia magna, was determined in accordance with the requirements of OECD Chemicals Testing Guideline No. 202 Daphnia sp. Acute Immobilisation Test (adopted April 13 2004).
As there was no valid analytical method available to measure the test substance concentration at the time of testing, the results were based on nominal loading rates.
Based on nominal loading rates, the 48-hour EC50 value was estimated to be >100 mg/L.
The corresponding NOEC value was 100 mg/L.
All validity criteria were satisfied, therefore the test was considered valid. - Conclusions:
- The 48-hour acute toxicity of Dioctyldodecyl Dodecanedioate to the freshwater planktonic crustacean, Daphnia magna, was determined in accordance with the requirements of OECD Chemicals Testing Guideline No. 202 Daphnia sp. Acute Immobilisation Test (adopted April 13 2004).
Based on nominal loading rates, the 48-hour EC50 value was estimated to be >100 mg/L.
The corresponding NOEC value was 100 mg/L.
All validity criteria were satisfied, therefore the test was considered valid. - Executive summary:
Product should not be classified according to CLP criteria for Acute or Chronic Hazards to the environment.
Reference
Description of key information
Based on result product should not be classified according to CLP criteria for Acute or Chronic Hazards to the environment.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- EC50
- Effect concentration:
- > 100 mg/L
Additional information
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