Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 619-799-8 | CAS number: 66309-83-9
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 14 Jul - 28 Jul 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- 92/69
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- 760 mg/L
- Conc. based on:
- test mat.
- Incubation duration:
- > 24 - < 72 h
- Temp.:
- 20 °C
- pH:
- 4.4 - 5.2
- Details on results:
- The key value is the mean of three experiments (duplicate measurements).
- Conclusions:
- The water solubility of the test substance is 760 mg/L at 20 °C.
- Executive summary:
The study was performed to assess the water solubility. The study was conducted in accordance with EEC Method for "determination of the water solubility", Directive 92/69/EEC, method A.6 which is in most parts equivalent to the OECD Guideline for Testing of Chemicals No. 105. The water solubility of test substance was determined with 760 mg/L at 20 °C.
Reference
Validity criteria for the measurement of the water solubility:
| Target condition according to guideline: | Actual condition according to the study: | Validity criteria met: |
A substance-specific analytical method is preferred for these determinations, since small amounts of soluble impurities can cause large errors in the measured solubility. Examples of such methods are: gas or liquid chromatography, titration methods, photometric methods, voltametric methods. | HPLC was used for analytical measurements | Yes |
| The pH of each sample should be recorded. | The pH was reported iin the range of 4.4 to 5.2 | Yes |
Shake flask:The individual results from each of the three flasks, which should not differ by more than 15%, are averaged. | The RSD was 2.3 % between the three flask. | Yes |
Description of key information
The study was performed to assess the water solubility. The study was conducted in accordance with EEC Method for "determination of the water solubility", Directive 92/69/EEC, method A.6 which is in most parts equivalent to the OECD Guideline for Testing of Chemicals No. 105. The water solubility of test substance was determined with 760 mg/L at 20 °C.
Key value for chemical safety assessment
- Water solubility:
- 760 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
