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EC number: 205-517-7 | CAS number: 141-98-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial plants: long-term
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction:US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- EPI Suite v 4.1/ECOSARv1.00
- GLP compliance:
- no
- Remarks:
- not applicable. QSAR model
- Analytical monitoring:
- not required
- Vehicle:
- no
- Species:
- other: Terrestrial plants,QSAR model
- Plant group:
- other: QSAR model
- Details on test organisms:
- no further information
- Test type:
- other: QSAR
- Study type:
- other: QSAR
- Substrate type:
- other: QSAR
- Limit test:
- no
- Total exposure duration:
- 30 d
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Moisture:
- not applicable. QSAR model
- Details on test conditions:
- SMILES : O(C(=NCC)S)C(C)C
CHEM : Carbamothioic acid, ethyl-, O-(1-methylethyl) ester
CAS Number: 141-98-0
MOL FOR: C6 H13 N1 O1 S1
MOL WT : 147.24
Log Kow: 3.32 (KowWin estimate)
Wat Sol: 114.4 mg/L (WskowWin estimate) - Reference substance (positive control):
- no
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 4.529 mg/kg soil dw
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Species:
- other: Terrestrial plants,QSAR model
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 2.156 mg/kg soil dw
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: cited as a ChV value, 1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Details on results:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 2.156 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 4.529 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same. - Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 2.156 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 4.529 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same. - Executive summary:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 2.156 mg/L (ppm) for terrestrial plants.
The ECOSAR QSAR model predicts that 96-hr EC50 valuewould to be 4.529 mg/L (ppm) for terrestrial plants.
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1977
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Justification for type of information:
- Propan-2-ol (Isopropyl alcohol) is both reagents used in the manufacture of IPETC/ O-isopropyl ethylthiocarbamate . Therefore, Propan-2-ol (Isopropyl alcohol) need to be considered in the assessment of IPETC/O-isopropyl ethylthiocarbamate .
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The inhibition of germination produced by the test compound applied in solution to a seed was determined. Inhibitory activity was expressed as the millimolar concentration of the compound producing 50 per cent inhibition at the given temperature.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on preparation and application of test substrate:
- The compound was applied in solution to a seed.
- Species:
- Lactuca sativa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- Details on test organisms
- Common name: garden lettuce
- Plant family: Asteraceae
- Variety: Great Lakes
- Source of seed: Sutton and Son Ltd.
- Prior seed treatment/sterilization: Not reported
- Historical germination of seed (germination of seed lot tested): Not reported
- Seed storage: Not reported - Test type:
- seed germination/root elongation toxicity test
- Study type:
- laboratory study
- Substrate type:
- not specified
- Limit test:
- no
- Total exposure duration:
- 3 d
- Test temperature:
- 30ºC
- pH:
- not reported
- Moisture:
- not reported
- Details on test conditions:
- not reported
- Nominal and measured concentrations:
- not reported
- Species:
- Lactuca sativa
- Duration:
- 3 d
- Dose descriptor:
- EC50
- Effect conc.:
- 2 100 other: mg/l
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- germination
- Remarks on result:
- other: 95% CL 35 ± 12 mM
- Details on results:
- EC50 ( 3 d) = 2100 mg/l (inhibition of seed germination)
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- A 3 d EC50 of 2100 mg/l has been determined for inhibition of seed germination to Lactuca sativa of the test substance.Propan-2-ol (Isopropyl alcohol) is both reagents used in the manufacture of IPETC/O-isopropyl ethylthiocarbamate. Therefore, Propan-2-ol (Isopropyl alcohol) need to be considered in the assessment of IPETC/ O-isopropyl ethylthiocarbamate .
- Executive summary:
A3 d EC50 of 2100mg/l has been determined for inhibition of seed germination to Lactuca sativaof the test substance.
Propan-2-ol (Isopropyl alcohol) is both reagents used in the manufacture of IPETC/O-isopropyl ethylthiocarbamateand .Therefore, Propan-2-ol (Isopropyl alcohol) need to be considered in the assessment of IPETC/O-isopropyl ethylthiocarbamate.
Referenceopen allclose all
Overview of QSARs estimations ontoxicity of O-isopropyl ethylthiocarbamate (IPETC ) to terrestrial plants
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Terrestrial plants ,96-hrEC50 = 4.529 mg/L (ppm) Terrestrial plants, 30-day, ChV (chronic value) =2.156 mg/L(ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Terrestrial plants ,96-hrEC50 = 4.529 mg/L (ppm)
Terrestrial plants, 30-day, ChV (chronic value) =2.156 mg/L(ppm)
1 kg of water has a volume of 1 L and the mg/kg and mg/L are the same.
Description of key information
A3 d EC50of2100mg/l has been determined for inhibition of seed germinationto Lactuca sativaof the test substance.
Propan-2 -ol (Isopropyl alcohol) is both reagents used in the manufacture of IPETC/O-isopropyl ethylthiocarbamate.Therefore, Propan-2-ol (Isopropyl alcohol) need to be considered in the assessment of IPETC/O-isopropyl ethylthiocarbamate
Key value for chemical safety assessment
- Short-term EC50 or LC50 for terrestrial plants:
- 2 100 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for terrestrial plants:
- 420 mg/kg soil dw
Additional information
A3 d EC50 of 2100mg/l has been determined for inhibition of seed germination to Lactuca sativa of the test substance.
Propan-2-ol (Isopropyl alcohol) is both reagents used in the manufacture of IPETC/ O-isopropyl ethylthiocarbamatea.Therefore, Propan-2-ol (Isopropyl alcohol) need to be considered in the assessment of IPETC/ O-isopropyl ethylthiocarbamate.
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