Registration Dossier
Registration Dossier
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EC number: 200-805-9 | CAS number: 74-11-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 008
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-chlorobenzoic acid
- EC Number:
- 200-805-9
- EC Name:
- 4-chlorobenzoic acid
- Cas Number:
- 74-11-3
- Molecular formula:
- C7H5ClO2
- IUPAC Name:
- 4-chlorobenzoic acid
- Test material form:
- solid
Constituent 1
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Test conditions
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 6.42 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 17.29 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Executive summary:
In a closed system algal toxicity test, the toxicity of benzoic acid and its derivatives on Pseudokirchneriella subcapitata was determined.
Median effective concentration values are 6.42 mg/l (EC50, final yield) and 17.29 mg/l (EC50, growth rate) for 4-chlorobenzoic acid.
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