Registration Dossier
Registration Dossier
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EC number: 838-538-0 | CAS number: 52139-31-8
Endpoint summary
Administrative data
Description of key information
According to Regulation (EC) No. 1907/2006 (REACH) Annex VII, section 9.2.1.1, column 2, the study does not need to be conducted because the substance is inorganic.
Additional information
The substance manganese monoglycinate sulfate is constituted of two main components, glycine and manganese sulfate. Manganese monoglycinate sulfate is considered to dissociate in aqueous solutions thus, in biodegradation screening tests the single components are tested. Manganese sulfate is inorganic and thus testing for biodegradation is technically not feasible. The other component glycine is an ubiquitously occurring amino acid which is known to be readily metaboilised by virtually every organism (common textbooks of biochemistry). Furthermore it was shown to be readily biodegraded by activated sludge (Carlson & Polkowski 1962; Malaney, 1969; Placak & Ruchhoft, 1947; Bernheim et al., 1935). Based on these information the amino acid salt manganese monoglycinate sulfate is not considered to be less biodegradabble than its main contsituent.
Carlson D.A., June l965, UTILIZATION OF FREE AND COMBINED AMINO ACIDS BY ACTIVATED SLUDGE
Dale A. Carlson and L. B. Polkowski, Journal (Water Pollution Control Federation), Vol. 34, No. 8 (Aug., 1962), pp. 816-829
Malaney GW and Gerhold RM, Warburg Tests, Vol. 41. No.2, Part 2, 1969
O. R. Placak and C. C. Ruchhoft, Sewage Works Journal, Vol. 19, No. 3 (May, 1947), pp. 423-440
Bernheim F, Bernheim MLC and Webster MD, OXIDATION OF CERTAIN AMINO ACIDS BY “RESTING” BACILLUS PROTEUS. J. Biol. Chem., 110, 165-172. 1935
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