Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to non-target arthropods on natural substrate (NTA other than pollinators)
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Description of key information
The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the toxicity to terrestrial arthropods.
Key value for chemical safety assessment
Additional information
In accordance with Regulation (EC) No 1907/2006, Annex X, column 2, 9.4 further studies on the effects on terrestrial organisms do not have to be conducted since short-term toxicity on soil macroorganism is available for a structurally and chemically closely related source substance showing no effects on survival or biomass during the exposure period.
Fatty acids, C16-18 (even numbered), esters with glycerol oligomers is characterised by a high log Koc (1.31 – 12.67, KOCWIN v2.00; MCI method) indicating a considerable potential for adsorption to soil particles. Therefore, tests with soil-dwelling organisms like earthworm which allows potential uptake via surface contact, soil particle ingestion and pore water (Guidance on information requirements and chemical safety assessment, Chapter R.7c, (ECHA, 2017)) are most relevant for the evaluation of soil toxicity of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers.
According to ECHA guidance (Chapter R.7c: Endpoint specific guidance, 2017) new long-term testing only needs to be conducted where the data on aquatic effects are insufficient to complete the Chemical Safety Assessment. Since acute aquatic toxicity data are available for structurally and chemically closely related source substances for all three trophic levels and chronic toxicity data are available for aquatic invertebrates and algae the Chemical Safety Assessment can be evaluated completely. All reliable aquatic acute and chronic data show no effects up to the water solubility limit. As all acute toxicity effects range above 10 mg/L and no chronic or long-term effects in aquatic organisms up to the water solubility limit were observed, this can be used to waive the data requirements of Annex IX (Chapter R.7c: Endpoint specific guidance, 2017, page 148).
As the substance is considered readily biodegradable (94% biodegradation after 28 days; read-across) confirmed with QSAR calculations for representative constituents (VEGA (1.1.4); Ready Biodegradability Model (v1.0.9)), it is expected that an extensive elimination of the substance in sewage treatment plants will occur. According to the Guidance on Information Requirements and Chemical Safety Assessment, Chapter R.7b (ECHA, 2017), the ready biodegradability of a substance can be considered indicative of rapid and ultimate degradation in most environments, including biological sewage treatment plants (STP) where the substance will be extensively removed in the primary settling tank and fat trap. As a result of the high adsorption potential of the substance (log Koc = 1.31 – 12.67, KOCWIN v2.00; MCI method), a removal from the water column to a significant degree by adsorption to sewage sludge can be expected (Guidance on information requirements and chemical safety assessment, Chapter R.7b, (ECHA, 2017)). Thus, only limited amounts will get in contact with activated sludge organisms in STPs and the concentration of the substance in effluents of conventional STPs is presumably marginal. Therefore, discharged concentrations of these substances into the soil compartment are likely to be negligible.Considering this, one can assume that the availability of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers in the soil environment is very low, which reduces the probability of exposure, in particular long-term exposure, of soil organisms in general.
Moreover, the bioaccumulation potential is low. Based on the physico/chemical properties such as poor water solubility and high potential for adsorption a reduced availability in water is expected. In addition, the available literature data showed that soil microorganisms are capable to break-up ester bonds and degrade fatty acids in significant amounts. Moreover, the data indicated the non-toxic properties of fatty acids since they can be used as energy source. It can be concluded that the bioaccumulation potential of Fatty acids, C16-18 (even numbered), esters with glycerol oligomers is negligible. This is supported by a low calculated BCF value ranged from 0.94 - 18.58L/kg ww (BCFBAF v3.01, Arnot-Gobas, including biotransformation, upper trophic).With VEGA 1.1.3 BCF values of 0.74 - 2 L/kg were determined (Caesar v2.1.14) for the main components of the substance.
In conclusion, no effects in a short-term toxicity study on soil macroorganisms were reported. Furthermore, no chronic or long-term effects in aquatic organisms up to the water solubility limit and no acute effects for aquatic organisms above 10 mg/L were determined. In addition, an extensive elimination of the substance in sewage treatment plants, a low bioavailability and a low bioaccumulation potential is expected for the target substance. Thus, no further study on the effects on terrestrial organisms need to be conducted for Fatty acids, C16-18 (even numbered), esters with glycerol oligomers.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.