Registration Dossier
Registration Dossier
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EC number: 500-013-6 | CAS number: 9004-78-8 1 - 2.5 moles ethoxylated
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vitro
- Type of information:
- other: expert assessment
- Adequacy of study:
- key study
- Study period:
- 2019
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Assessment based on the properties of the indvidiual constituents of the substance
Data source
Reference
- Reference Type:
- other: expert assessment
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- An assessment was conducted based on the properties of the indvidiual constituents of the substance.
- GLP compliance:
- no
- Type of study:
- other: Assessment based on the properties of the indvidiual constituents of the substance
Test material
- Reference substance name:
- Phenol, ethoxylated
- EC Number:
- 500-013-6
- EC Name:
- Phenol, ethoxylated
- Cas Number:
- 9004-78-8
- Molecular formula:
- not applicable - the substance is a multiconstituent substance
- IUPAC Name:
- 2-phenoxyethan-1-ol
- Test material form:
- liquid
Constituent 1
Results and discussion
In vitro / in chemico
Results
- Remarks on result:
- other: An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- An assessment was conducted based on the properties of the indvidiual constituents of the substance. It concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.
- Executive summary:
The capacity of Phenol, ethoxylated to induce skin sensitisation was assessed based on the available information on its constituents.
2-phenoxyethanol and 2-(2-phenoxyethoxy)ethanol are not classified as sensitising to the skin based on available experimental data.
Considering the structural similarities between the constituents of Phenol, ethoxylated and in the absence of experimental data on the substance, 2-[2-(2-phenoxyethoxy)ethoxy]ethanol is not expected to induce skin sensitisation.
It is concluded that Phenol, ethoxylated does not meet the criteria for classification as sensitising to the skin according to the CLP Regulation.
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