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Diss Factsheets
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EC number: 218-191-6 | CAS number: 2068-80-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- - Principle of test:
Determination of oxygen uptake/oxidation of the compound using the Warburg respirometer
- Short description of test conditions:
Exposure of individual chemical compounds at a concentration of 500 mg/l to activated sludge solids at 2,500 mg/l in the Warburg respirometer with oxygen uptake as the measure of oxidation of the compound. The theoretical oxygen demand (TOD) is defined as the concentration of oxygen in mg/L required to oxidize 500 mg/L of substrate completely, i.e., to CO2, water, nitrate, sulfate, and chlorate. - GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Duration of test (contact time):
- 24 h
- Initial conc.:
- 500 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Remarks:
- percent from TOD
- Reference substance:
- other: no
- Key result
- Parameter:
- % degradation (O2 consumption)
- Remarks:
- percent of TOD
- Value:
- 28.8
- Sampling time:
- 24 h
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- readily biodegradable
- Conclusions:
- In the present study of Malaney and Gerhold the biological oxygen demand, i.e. the concentration of oxygen in mg/L required to oxidize 500 mg/L of substrate completely, of activated sludge incubated with DL-aspartic acid was determined. The result reveals that 28.8 % of the compound were degraded within 24 h, therefore DL-aspartic acid is considered to be readily biodegradable.
Reference
Description of key information
Based on the published data from Malaney (1969) aspartic acid is readily biodegradable. The additionally contained magnesium in the test item is not considered to have any impact on biodegradability. Furthermore, according to Regulation (EC) No. 1907/2006 (REACh) there is no need for biodegradability testing of magnesium because the susbtance in an inorganic.
Key value for chemical safety assessment
Additional information
Based on the published data from Malaney (1969) aspartic acid is readily biodegradable. The additionally contained magnesium in the test item is not considered to have any impact on biodegradability. Furthermore, according to Regulation (EC) No. 1907/2006 (REACh) there is no need for biodegradability testing of magnesium because the susbtance in an inorganic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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