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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Supporting study. Data from peer-rewieved handbook. The LD50 for rats was 11450 mg/kg.

Supporting study. Data from peer-rewieved handbook. The LD50 for mice was 320 mg/kg.

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records

Referenceopen allclose all

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
secondary literature
Principles of method if other than guideline:
Data from peer-rewieved hadndbook
GLP compliance:
not specified
Species:
rat
Route of administration:
oral: unspecified
Sex:
not specified
Dose descriptor:
LD50
Effect level:
11 450 mg/kg bw
Interpretation of results:
study cannot be used for classification
Conclusions:
The LD50 was 11450 mg/kg.
Executive summary:

Data from a peer-reviewed handbook is available. The LD50 was 11450 mg/kg.

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
secondary literature
Principles of method if other than guideline:
Data from peer-rewieved hadndbook
GLP compliance:
not specified
Species:
mouse
Route of administration:
oral: unspecified
Sex:
not specified
Dose descriptor:
LD50
Effect level:
320 mg/kg bw
Interpretation of results:
study cannot be used for classification
Conclusions:
The LD50 was 320 mg/kg.
Executive summary:

Data from a peer-reviewed handbook is available. The LD50 was 320 mg/kg.

Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
320 mg/kg bw

Additional information

Justification for classification or non-classification