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Diss Factsheets
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EC number: 602-997-3 | CAS number: 124495-18-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
No significant hydrolytic degradation was observed to occur in pH buffers 5, 7 or 9 at 50°C. Less than 10% hydrolysis was observed at 5 days which by the guidelines defines the substance as hydrolytically stable (t1/2> 1 year). In another test at pH 4, the test substance degraded at 25°C with a t1/2 of 11 weeks, decreasing to ca 2 weeks at 40°C and in a third test, the half-life at pH 4 and 50°C was 5 days. 5,7-dichloro-4-hydroxyquinoline (DCHQ) was found to be the hydrolysis product. In phototransformation studies in water, the test substance degraded with a ½ life of 18 minutes. CFBPQ (2-chloro-10-fluoro[1]benzopyrano[2,3,4-de]quinoline) was identified as the primary photodegradate of the test substance.
CFBPQ is formed very quickly under natural conditions. Once formed there is a rapid degradation of CFBPQ to material which is polar and multicomponent in nature. When sediment is present the amount of radioactivity present in the aqueous layer is greatly reduced due to partitioning of CFBPQ to the sediment. Low water solubility combined with rapid aqueous photolysis suggest that the test substance will have minimal impact on the aquatic environment. The t1/2 estimated for test substance under natural sunlight conditions (>1 year; spring at Letcombe, England) has indicated that soil photolysis will not be a significant route of degradation for the test substance in the environment.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.