Registration Dossier
Registration Dossier
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EC number: 232-167-2 | CAS number: 7789-45-9
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
Data source
Reference
- Reference Type:
- other: internet website
- Title:
- Unnamed
- Year:
- 2 006
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Classification was made according to GHS Classification Manual (10 Feb, 2006).
- GLP compliance:
- no
Test material
- Reference substance name:
- Hydrogen bromide
- EC Number:
- 233-113-0
- EC Name:
- Hydrogen bromide
- Cas Number:
- 10035-10-6
- Molecular formula:
- BrH
- IUPAC Name:
- bromide
Constituent 1
Results and discussion
In vivo
Results
- Irritation parameter:
- other: eye membrane stimulus
- Reversibility:
- not reversible
- Remarks on result:
- probability of severe irritation
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (irreversible effects on the eye) based on GHS criteria
- Conclusions:
- As bromide ion is more hazardous than cupric ion, the toxicological data has been provided for bromide.
HBr was set as Category 1 based on the report (DFGOT vol.13 (1999)) of the serious eye membrane stimulus by humans (DFGOT vol.13 (1999)), and a statement called corrosiveness (ICSC (J), (2001)).
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