4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Guidance on Safe Use

First-aid measures

Eye Contact: Flush with water while holding eyelids open for at least 15 minutes.  Seek medical attention immediately.

Skin Contact: Remove contaminated clothing.  Flush area with large amounts of water.  Use soap.  Seek medical attention.

Ingestion: Never give anything by mouth to an unconscious person.  Wash out mouth with water.  Do not induce vomiting unless directed by medical personnel.  Seek medical attention immediately.

Inhalation: Remove to fresh air and keep patient at rest.  Seek medical attention immediately.

Fire-fighting measures

- Suitable extinguishing media:

Extinguish fires with CO2, extinguishing powder, foam, or water.

- Special hazards arising from the substance or mixture: Dust can form an explosive mixture in air. Fine particles (such as dust and mists) may fuel fires/explosions.

Hazardous Combustion Products: formation of toxic gases is possible during heating or fire.  May include oxides of carbon and

nitrogen and products of chlorine.

- Advice for fire fighter: During all fire fighting activities, wear appropriate protective equipment, including self-contained breathing apparatus.

Accidental release measures

- Personal precautions:

  Minimize exposure. Non-essential personnel should be evacuated from affected area.  Report emergency situations immediately.  Clean up operations should only be undertaken by trained personnel.

- Protective equipment and emergency procedures:

Personnel involved in clean-up should wear appropriate personal protective equipment..

- Environmental precautions:

Place waste in an appropriately labeled, sealed container for disposal.  Care should be taken to avoid environmental release.

- Methods and material for containment and cleaning up: Contain the source of the spill if it is safe to do so. Collect spilled material by a method that

controls dust generation. Avoid use of a filtered vacuum to clean spills of dry solids. Clean spill area thoroughly.  

Handling and storage

- Precautions for safe handling:

Ground and bond all bulk transfer equipment. Avoid open handling. Minimize dust generation. Use local exhaust ventilation or perform work under fume hood/fume cupboard. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal protective equipment. Wash hands and any exposed skin after removal of PPE. Releases to the environment should be avoided.  Review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure or environmental releases.  Potential points of process emissions of this material to the atmosphere should be controlled with dust collectors, HEPA filtration systems or other equivalent controls

- Conditions for safe storage, including any incompatibilities: Store at room temperature in properly labeled containers.  Keep away from heat, sparks and flames.

Transport information

Shipping

SpecialProvisions

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

1. Technical protection measures: Engineering controls should be used as the primary means to control exposures.  Use process

containment, local exhaust ventilation, or other engineering controls to maintain airborne levels within the upational Exposure Band (OEB) range.

2. Organisational protection measures: Owing to the absence of health hazard characterization data, this material should be handled according to procedures designed to provide protection from known or unknown hazards. Compnies OEB 3 - Contact Hazards Unknown (control exposure to the range of 10ug/m3 to < 100ug/m3.)

3. Hand protection: Wear impervious gloves (e.g. Nitrile, etc.) as minimum protection.  (Protective gloves must meet the standards in accordance with EN374, ASTM F1001 or international equivalent.)

4. Body protection: Wear impervious protective clothing when handling this compound.  (Protective clothing must meet the standards in accordance with EN13982, ANSI 103 or international equivalent.).

5. Eye protection: Wear safety glasses as minimum protection. (Safety glasses must meet the standards in

accordance with EN166, ANSI Z87.1 or international equivalent.)

7. Respiratory protection: Under normal conditions of use, if the applicable Occupational Exposure Band (OEB) is exceeded, wear an appropriate respirator with a protection factor sufficient to control exposures to below the OEB (e.g. particulate respirator with a half mask, P3 filter).  (Respirators must meet the standards in accordance with EN140, EN143, ASTM F2704-10 or international

equivalent.)

Stability and reactivity

1. Reactivity

: No data available

2. Chemical stability

: Stable under normal conditions of use

3. Conditions to avoid

: Unknown.  Fine particles (such as dust and mists) may fuel fires/explosions. As a precautionary measure, keep away from heat sources and electrostatic discharge.

4. Incompatible materials: Unknown As a precautionary measure, keep away from strong oxidizers

5. Hazardous decomposition products: No data available

Disposal considerations

Waste Treatment Methods:

Dispose of waste in accordance with all applicable laws and regulations.  Member State specific and Community specific provisions must be considered.  Considering the relevant known environmental and human health hazards of the material, review and implement appropriate technical and procedural waste water and waste disposal measures to prevent occupational exposure and environmental release.  It is recommended that waste minimization be practiced.  The best available technology should  be utilized to prevent environmental releases. This may include destructive techniques for waste and wastewater.