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EC number: 832-253-5 | CAS number: 12165-18-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 22 October 2007 - 6 May 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
- Water solubility:
- 1.27 mg/L
- Conc. based on:
- test mat. (dissolved fraction)
- Remarks:
- recalculated based on measured dissolved Pr concentrations
- Temp.:
- 20 °C
- pH:
- >= 6.59 - <= 6.76
- Water solubility:
- 1.035 mg/L
- Conc. based on:
- element (dissolved fraction)
- Remarks:
- dissolved Pr
- Temp.:
- 20 °C
- pH:
- >= 6.59 - <= 6.76
- Details on results:
- The measured results differ by less than 30%. Therefore, the study is considered to be valid.
- Conclusions:
- The water solubility of the test material at 20°C was determined to be 1.27 mg/L (standard deviation ± 0.10 mg/L) using the column elution method.
- Endpoint:
- water solubility
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Justification for type of information:
- Read across from studies performed with the individual constituents of the reaction mass, i.e. praseodymium(III,IV) oxide and zirconium dioxide. The read across justification document is attached to IUCLID Section 13.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Remarks on result:
- other: Based on data obtained for the individual constituents of the reaction mass, it can be concluded that the reaction mass of praseodymium(III,IV) oxide and zirconium dioxide is a substance of poor water solubility.
- Remarks:
- The water solubility of praseodymium(III,IV) oxide was determined to be 1.27 mg/L (equivalent to 1.035 mg Pr/L) whereas that of zirconium dioxide was determined to be < 55 µg/L (equivalent to < 41 µg Zr/L). Consequently, the reaction mass of praseodymium(III,IV) oxide and zirconium dioxide is not expected to give rise to dissolved praseodymium or zirconium concentrations higher than these respective concentrations measured in these studies.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 2008-02-25 to 2010-09-03
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- certificate provided by Rheinlandpfalz
- Type of method:
- column elution method
- Water solubility:
- < 55 µg/L
- Temp.:
- 20 °C
- pH:
- 6.5
- Details on results:
- Limit of detection was calculated from the calibrated range to be 40.8 µg/L Zr, corresponding to 55 µg/L ZrO2. As none of the samples showed a signal at the voltage of the Zr-Alizarin-peak, concentration in the samples and therefore water solubility was considered to lie below LOD.
No observations arousing doubts concerning the accuracy of the results and the validity of the study were made. - Conclusions:
- The water solubility of the test item was found to be < 55 µg/L at a temperature of 20 +/- 0.5 degrees C and a pH of 6.5.
Referenceopen allclose all
Table 1: Water solubility (Column Elution Method)
Experiment No. |
Flow rate (mL/h) |
Sample No. |
Concentra- tion analysed * (mg Pr/L) |
Water solubility calculated (mg Test material/L) |
Water solubility calculated (mg Test material/L) |
Water solubility calculated (mg Test material/L) |
pH |
1 |
31 |
1 2 3 4 5 |
1.04* 1.04* 1.04* 1.03* 1.03* |
1.36 1.36 1.36 1.35 1.35 |
1.35 SD = ± 0.007 |
1.27 SD = ± 0.10 |
6.66 6.70 6.59 6.76 6.63 |
2 |
16 |
6 7 8 9 10 11 |
0.92* 0.91* 0.89* 0.89* 1.01* 0.83* |
1.20 1.19 1.16 1.16 1.32 1.08 |
1.19 SD = ± 0.08 |
6.69 6.71 6.70 6.75 6.68 6.72 |
SD = Standard deviation
* Values measured by ICP / MS
Description of key information
No experimental information is available on the water solubility of dipraseodymium dizirconium heptaoxide.
However, based on a weight of evidence approach including data obtained for its individual constituents, the substance can be concluded to be poorly soluble in water at room temperature and circumneutral pH. The water solubility of praseodymium(III,IV) oxide was determined to be 1.27 mg/L (equivalent to 1.035 mg Pr/L) whereas that of zirconium dioxide was determined to be < 55 µg/L (equivalent to < 41 µg Zr/L).
Consequently, dipraseodymium dizirconium heptaoxide is not expected to give rise to dissolved praseodymium or zirconium concentrations higher than these respective concentrations measured in these studies.
Key value for chemical safety assessment
Additional information
1. Information on praseodymium(III,IV) oxide
Based on a guideline study (Weissenfeld, 2008; Klimisch 1), the water solubility of praseodymium(III,IV) oxide at 20°C was determined to be 1.27 mg/L (equivalent to 1.035 mg Pr/L). The pH measured in the test samples ranged from 6.59 to 6.76.
2. Information on zirconium dioxide
Based on a guideline study (Paulus, 2010; Klimisch 1), the water solubility of zirconium dioxide was found to be < 55 µg/L at a temperature of 20 +/- 0.5°C and a pH of 6.5. When expressed as zirconium concentration the water solubility was < 41 µg Zr/L.
3. Conclusion on the substance dipraseodymium dizirconium heptaoxide
Based on the data obtained for its individual constituents, the substance dipraseodymium dizirconium heptaoxide can be concluded to be poorly soluble in water at room temperature and circumneutral pH.
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