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EC number: 227-367-1 | CAS number: 5807-14-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72-hour ErC50 = 32 mg/L, NOEC = 3.2 mg/L, LOEC = 10 mg/L, US EPA OCSPP 850.4500 and OPPTS 850.1000
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 32 mg/L
Additional information
A study was performed to assess the effect of the test material on the growth of the green alga Pseudokirchneriella subcapitata.The study was conducted in accordance with the standardised guidelines US EPA OCSPP 850.4500 and the US EPA OPPTS 850.1000 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Following preliminary range-finding tests, Pseudokirchneriella subcapitata was exposed to an aqueous solution of the test material at concentrations of 1.0, 3.2, 10, 32 and 100 mg/L (four replicate flasks per concentration) for 96 hours, under constant illumination and shaking at a temperature of 24 ± 1 °C.
Due to the highly alkaline nature of the test material, the pH of the test preparations was adjusted to pH 7.5 prior to inoculation with algal cells at the beginning of the test in order to determine the true toxic effect of the test material.
Samples of the algal populations were removed daily and cell concentrations determined for each control and treatment group, using a Coulter® Multisizer Particle Counter.
Analysis of the test preparations at 0, 72 and 96 hours showed measured test concentrations to range from 99 to 123 % of nominal and so the results are based on nominal test concentrations only.
The growth rate (r), yield (y) and biomass integral (b) were affected by the presence of the test material over the 96-hour exposure period.
Under the conditions of this study, the 72 hour ErC50 was 32 mg/L (95 % Confidence Limits 27 - 39 mg/L). The NOEC and LOEC were 3.2 and 10 mg/L, respectively. A re-growth test was performed which showed the test material to be algistatic in effect.
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