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EC number: 237-997-9 | CAS number: 14154-09-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 60, 140, 240 mg/L
- Sample storage conditions before analysis: Solutions were acidified with HNO3 for stabilisation, samples were analysed immediately after sampling or (if immeidate anaysis not possible) stored at 4°C. - Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: The test solutions were prepared according to OECD guidance No. 23. The test solutions were prepared separately by adding the required amount of substance to the test medium. the solutions were stirred for 24 hours and subsequently filtered (0.2 µm filter). - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Source: German Federal Environment Agency, Institut für Wasser-, Boden- und Lufthygiene. Specimens used in the test were bred in the laboratory of the Fraunhofer IME.
- Age at study initiation (mean and range, SD): 4-24 h
- Feeding during test: no - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 1.2 - 1.3 mmol/L
- Test temperature:
- 19.6 - 19.7 °C
- pH:
- 8.1 - 8.3
- Dissolved oxygen:
- 7.8 - 8.9 mg/L
- Nominal and measured concentrations:
- Nominal test substance concentrations: 60, 120, and 240 mg/L (corresponding to 22.9, 45.7 and 91.4 mg Mn/L)
Measured Mn concentrations test start: 1.24, 2.02, 2.10 mg Mn/L (corresponding to 3.72, 5.31, 5.52 mg test substance/L)
Measured Mn concentrations test end: 0.74, 1.68, 2.18 mg mn/L (corresponding to 1.95, 4.41, 5.73 mg test substance/L) - Details on test conditions:
- TEST SYSTEM
- Test vessel: glass beakers (50 mL)
- Fill volume: 50 mL
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Purified drinking water.
- Alkalinity: 2.0 - 2.4 mmol/L
- Conductivity: 227 - 224 µs/cm
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16:8 h day-night regime
- Light intensity: 763 - 823 Lx
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
Mobility after 0, 24 and 48 h
TEST CONCENTRATIONS
- Range finding study
- Test concentrations: 60, 120, 240 mg/L
- Results used to determine the conditions for the definitive study: EC50>240 mg/L - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 5.63 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- test mat.
- Remarks:
- recaluclated from measured Mn concentration
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 5.63 mg/L
- Nominal / measured:
- meas. (geom. mean)
- Conc. based on:
- element
- Remarks:
- Mn concentration
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 240 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 240 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- - Behavioural abnormalities: no
- Mortality of control: no - Reported statistics and error estimates:
- No statistic test was performed since no daphnids died during the study.
Reference
Description of key information
Not acutely toxic to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The acute toxicity of trimanganese bis(orthophosphate) (CAS 14154-09-7) to aquatic invertebrates was investigated in a study conducted according to OECD guideline 202. Daphnia magna were exposed to nominal test substance concentrations of 60, 120, and 240 mg/L for 48 hours. The test concentrations were prepared separately by applying the Water Accommodated Fraction (WAF) approach according to the OECD guidance No. 23 and 29. The concentrations of trimanganese bis(orthophosphate) in the test media were determined by chemical analyses of manganese in the aqueous phase at the start and at the end of the test using ICP-OES (LOQ 9.78 μg Mn/L). The test substance concentrations were recalculated from the measured manganese concentrations. An immobilization of the Daphnids was not observed at any tested concentrations. After 48 hours of exposure an EC50(48 h) >5.63 mg/L (mean measured) was determined. Based on the nominal substance concentration an EC50(48h) > 204 mg/L was recorded (EC50(48 h).
Based on the experimental results trimanganese bis(orthophosphate) is not acutely toxic to aquatic invertebrates.
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