Registration Dossier
Registration Dossier
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EC number: 220-168-0 | CAS number: 2650-18-2
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
NOEC Daphnia > 10 mg/L
LOEC Daphnia > 10 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 10 mg/L
Additional information
The following data were obtained for Similar Substance 1. It is expected that the Target substance will present similar effect levels in long term toxicity studies on aquatic invertebrates. Justification for Read Across is given in Section 13 of IUCLID.
A GLP guideline study according OECD 211 has been conducted. For the limit test (test concentration of 10 mg/L) a semi-static test design was chosen using a renewal of 3 times per week. Daphnia magna has been exposed for 21 d and the effects on reproduction have been evaluated.
No significant mortality or reduced reproduction were observed in any of the test treatments. Therefore, the data were not sufficient to calculate ECx values for reproduction or mortality.
Since the analytically determined concentrations of the test substance in the test solutions were within the range of ± 20 % of the nominal concentrations, the effect concentration can be expressed relative to the nominal concentration. The LOEC was determined to be > 10 mg/L and the NOEC was determined to be >= 10 mg/L. Therefore, the test substance is not harmful to aquatic invertebrates in long term studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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