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EC number: 270-471-7 | CAS number: 68441-67-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 Feb. 2017 to 07 Apr. 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- OECD Guidelines for the Testing of Chemicals, Method No. 104, adopted 23. Mar. 2006: “Vapour Pressure“
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Council Regulation (EC) No 761/2009 of 24 August 2009, Method A.4: “Vapour Pressure”
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- No further details specified in the study report.
- Key result
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- For the test item Hatcol 3178, the following vapour pressures at 20°C and at 25°C were calculated from the regression equation:
Vapour pressure at 20°C: 1.93 * 10-08 Pa
Vapour pressure at 25°C: 4.28 * 10-08 Pa
The linear regression of log P vs. 1/T gave a correlation coefficient r of - 0.9971, showing good repeatability and precision. Therefore, the determination is considered as valid. - Executive summary:
This study was performed in order to determine the vapour pressure of Hatcol 3178. The vapour pressure is one of the physical-chemical properties of a substance and needed for risk assessments. The method is based on the estimation of the mass of test item flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of effused vapour is obtained by determining the loss of mass of the cell. The vapour pressure is calculated by applying the Hertz-Knudsen relation. The recommended range is 10–10to 1 Pa.
The vapour pressure of Hatcol 3178 was determined following EU A.4 using the effusion method (weight loss).
Vapour pressure was examined at nine different temperatures. Three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (P).
Vapour Pressures (Effusion Method)
Experiment
T
Mean P
Stand. Dev. P
RSD P
No.
K
Pa
Pa
%
7
393.2
3.65E-03
1.05E-03
28.7%
8
408.2
1.14E-02
1.14E-03
10.0%
9
423.2
4.52E-02
4.95E-03
11.0%
In this table, E-0X represents multiplication with 10-X.
Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation
The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of - 0.9971.
For the test item Hatcol 3178, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.93 * 10-08Pa
Vapour pressure at 25 °C: 4.28 * 10-08Pa
Reference
Sample Weights
The mass of sample in the respective cell is presented in the following table:
Parameter |
Cell empty |
Cell + test item |
Cell + test item + cap |
Test item |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
2.58925 |
3.65459 |
3.90980 |
1.06534 |
Knudsen-cell 2 |
2.60780 |
3.79185 |
4.04527 |
1.18405 |
Knudsen-cell 3 |
2.58065 |
3.65176 |
3.91139 |
1.07111 |
Knudsen-cell 4 |
2.59670 |
3.74607 |
4.00032 |
1.14937 |
Measurement Data
The data of the evaluated experiments is present in the following tables:
Measurement Data Experiment 1
Experiment |
1 |
|
|
|
Nominal Temperature |
30 |
°C |
|
|
Date and time START |
|
21.02.2017 12:10 |
22.02.2017 13:15 |
23.02.2017 12:25 |
Date and time END |
|
22.02.2017 12:35 |
23.02.2017 11:30 |
24.02.2017 12:00* |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90980 |
3.90944 |
3.90956 |
3.90953 |
Knudsen-cell 2 |
4.04527 |
4.04497 |
4.04497 |
4.04503 |
Knudsen-cell 3 |
3.91139 |
3.91113 |
3.91113 |
3.91114 |
Knudsen-cell 4 |
4.00032 |
3.99999 |
4.00005 |
4.00000 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 2
Experiment |
2 |
|
|
|
Nominal Temperature |
45 |
°C |
|
|
Date and time START |
|
27.02.2017 11:50 |
28.02.2017 12:55 |
01.03.2017 12:35 |
Date and time END |
|
28.02.2017 11:50 |
01.03.2017 11:30 |
02.03.2017 11:45 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90953 |
3.90958 |
3.90978 |
3.90976 |
Knudsen-cell 2 |
4.04503 |
4.04508 |
4.04530 |
4.04525 |
Knudsen-cell 3 |
3.91114 |
3.91130 |
3.91145 |
3.91136 |
Knudsen-cell 4 |
4.00000 |
4.00022 |
4.00040 |
4.00037 |
Measurement Data Experiment 3
Experiment |
3 |
|
|
|
Nominal Temperature |
60 |
°C |
|
|
Date and time START |
|
02.03.2017 13:55 |
06.03.2017 12:10 |
07.03.2017 12:40 |
Date and time END |
|
03.03.2017 11:50* |
07.03.2017 11:50 |
08.03.2017 12:10 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90976 |
3.90976 |
3.90976 |
3.90988 |
Knudsen-cell 2 |
4.04525 |
4.04548 |
4.04548 |
4.04555 |
Knudsen-cell 3 |
3.91136 |
3.91155 |
3.91155 |
3.91182 |
Knudsen-cell 4 |
4.00037 |
4.00037 |
4.00037 |
4.00038 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 4
Experiment |
4 |
|
|
|
Nominal Temperature |
75 |
°C |
|
|
Date and time START |
|
08.03.2017 12:50 |
09.03.2017 11:55 |
13.03.2017 12:00 |
Date and time END |
|
09.03.2017 11:00 |
10.03.2017 10:05* |
14.03.2017 11:45 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90988 |
3.90989 |
3.90988 |
3.90988 |
Knudsen-cell 2 |
4.04555 |
4.04554 |
4.04552 |
4.04552 |
Knudsen-cell 3 |
3.91182 |
3.91181 |
3.91182 |
3.91182 |
Knudsen-cell 4 |
4.00038 |
4.00037 |
4.00036 |
4.00036 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 5
Experiment |
5 |
|
|
|
Nominal Temperature |
90 |
°C |
|
|
Date and time START |
|
14.03.2017 12:50 |
15.03.2017 12:35 |
16.03.2017 11:25 |
Date and time END |
|
15.03.2017 11:45 |
16.03.2017 10:45 |
17.03.2017 11:50* |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90988 |
3.91016 |
3.91016 |
3.91009 |
Knudsen-cell 2 |
4.04552 |
4.04588 |
4.04588 |
4.04588 |
Knudsen-cell 3 |
3.91182 |
3.91199 |
3.91199 |
3.91192 |
Knudsen-cell 4 |
4.00036 |
4.00084 |
4.00084 |
4.00063 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 6
Experiment |
6 |
|
|
|
Nominal Temperature |
105 |
°C |
|
|
Date and time START |
|
20.03.2017 12:00 |
21.03.2017 12:40 |
22.03.2017 12:40 |
Date and time END |
|
21.03.2017 11:50 |
22.03.2017 11:40 |
23.03.2017 11:45 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.91009 |
3.90893 |
3.90746 |
3.90746 |
Knudsen-cell 2 |
4.04588 |
4.04469 |
4.04324 |
4.04324 |
Knudsen-cell 3 |
3.91192 |
3.91103 |
3.90934 |
3.90934 |
Knudsen-cell 4 |
4.00063 |
3.99936 |
3.99772 |
3.99772 |
Measurement Data Experiment 7
Experiment |
7 |
|
|
|
Nominal Temperature |
120 |
°C |
|
|
Date and time START |
|
23.03.2017 12:30 |
27.03.2017 12:20 |
28.03.2017 12:40 |
Date and time END |
|
24.03.2017 10:50* |
28.03.2017 11:45 |
29.03.2017 11:50 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90746 |
3.90570 |
3.90401 |
3.90300 |
Knudsen-cell 2 |
4.04324 |
4.04108 |
4.03995 |
4.03903 |
Knudsen-cell 3 |
3.90934 |
3.90581 |
3.90361 |
3.90249 |
Knudsen-cell 4 |
3.99772 |
3.99553 |
3.99375 |
3.99278 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 8
Experiment |
8 |
|
|
|
Nominal Temperature |
135 |
°C |
|
|
Date and time START |
|
29.03.2017 12:35 |
30.03.2017 12:45 |
03.04.2017 12:25 |
Date and time END |
|
30.03.2017 11:55 |
31.03.2017 11:50* |
04.04.2017 12:00 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.90300 |
3.89903 |
3.89619 |
3.89263 |
Knudsen-cell 2 |
4.03903 |
4.03496 |
4.03210 |
4.02877 |
Knudsen-cell 3 |
3.90249 |
3.89822 |
3.89547 |
3.89128 |
Knudsen-cell 4 |
3.99278 |
3.98821 |
3.98297 |
3.97796 |
*Due to organizational reasons, the samples were stored in an exsiccator after weighing until the start of the next measurement series.
Measurement Data Experiment 9
Experiment |
9 |
|
|
|
Nominal Temperature |
150 |
°C |
|
|
Date and time START |
|
04.04.2017 20:40 |
05.04.2017 12:40 |
06.04.2017 10:15 |
Date and time END |
|
05.04.2017 12:00 |
06.04.2017 09:30 |
07.04.2017 07:00 |
Parameter |
Weight m |
Weight m |
Weight m |
Weight m |
Unit |
g |
g |
g |
g |
Knudsen-cell 1 |
3.89263 |
3.87780 |
3.86281 |
3.85070 |
Knudsen-cell 2 |
4.02877 |
4.01500 |
4.00106 |
3.98979 |
Knudsen-cell 3 |
3.89128 |
3.87835 |
3.86517 |
3.85452 |
Knudsen-cell 4 |
3.97796 |
3.95959 |
3.94131 |
3.92696 |
Observations
120 °C: At the first measurement of experiment 7, all cells were slightly contaminated. Therefore, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
120 °C: At the second measurement of experiment 7, cell 3 was slightly contaminated. Therefore, the cell was meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, this measurement was not used for calculations.
Calculation Results
All calculation results are given below.
In all tables, E-0X represents multiplication with 10-x. The first six experiments showed no relevant or reproducible weight loss. Therefore, they were not used for the calculation of the result.
Calculation Results Experiment 7
Experiment |
7 |
|
|
|
|
|
|
|
|
Real Temperature in K |
393.2 |
|
|
|
|
|
|
|
|
Real Temperature in °C |
120.0 |
|
|
|
|
|
|
|
|
Date of Measurement |
24.03.2017 10:50 |
28.03.2017 11:45 |
29.03.2017 11:50 |
||||||
Elapsed Time in s |
80400 |
84300 |
83400 |
||||||
Parameter |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Unit |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
Knudsen-cell 1 |
0.00176 |
yes |
5.28E-03 |
0.00169 |
yes |
4.84E-03 |
0.00101 |
yes |
2.92E-03 |
Knudsen-cell 2 |
0.00216 |
yes |
6.48E-03 |
0.00113 |
yes |
3.23E-03 |
0.00092 |
yes |
2.66E-03 |
Knudsen-cell 3 |
0.00353 |
yes |
1.06E-02 |
0.00220 |
no |
|
0.00112 |
yes |
3.24E-03 |
Knudsen-cell 4 |
0.00219 |
yes |
6.57E-03 |
0.00178 |
yes |
5.10E-03 |
0.00097 |
yes |
2.81E-03 |
Mean |
|
no |
|
|
yes |
4.39E-03 |
|
yes |
2.91E-03 |
Standard deviation: |
|
|
|
|
|
1.01E-03 |
|
|
2.46E-04 |
Mean of measured values: |
|
3.649E-03 |
|
|
|
|
|
|
|
Standard deviation: |
|
1.048e-03 |
RSD: |
|
28.7% |
|
|
|
Calculation Results Experiment 8
Experiment |
8 |
|
|
|
|
|
|
|
|
Real Temperature in K |
408.2 |
|
|
|
|
|
|
|
|
Real Temperature in °C |
135.0 |
|
|
|
|
|
|
|
|
Date of Measurement |
30.03.2017 11:55 |
31.03.2017 11:50 |
04.04.2017 12:00 |
||||||
Elapsed Time in s |
84000 |
83100 |
84900 |
||||||
Parameter |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Unit |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
Knudsen-cell 1 |
0.00397 |
yes |
1.16E-02 |
0.00284 |
yes |
8.40E-03 |
0.00356 |
yes |
1.03E-02 |
Knudsen-cell 2 |
0.00407 |
yes |
1.19E-02 |
0.00286 |
yes |
8.46E-03 |
0.00333 |
yes |
9.64E-03 |
Knudsen-cell 3 |
0.00427 |
yes |
1.25E-02 |
0.00275 |
yes |
8.14E-03 |
0.00419 |
yes |
1.21E-02 |
Knudsen-cell 4 |
0.00457 |
yes |
1.34E-02 |
0.00524 |
yes |
1.55E-02 |
0.00501 |
yes |
1.45E-02 |
Mean |
|
yes |
1.24E-02 |
|
yes |
1.01E-02 |
|
yes |
1.16E-02 |
Standard deviation: |
|
|
7.74E-04 |
|
|
3.59E-03 |
|
|
2.18E-03 |
Mean of measured values: |
|
1.138E-02 |
|
|
|
|
|
|
|
Standard deviation: |
|
1.138E-03 |
RSD: |
|
10.0% |
|
|
|
Calculation Results Experiment 9
Experiment |
9 |
|
|
|
|
|
|
|
|
Real Temperature in K |
423.2 |
|
|
|
|
|
|
|
|
Real Temperature in °C |
150.0 |
|
|
|
|
|
|
|
|
Date of Measurement |
05.04.2017 12:00 |
06.04.2017 09:30 |
07.04.2017 07:00 |
||||||
Elapsed Time in s |
84000 |
75000 |
74700 |
||||||
Parameter |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Weight loss |
To be used |
Vapour pressure |
Unit |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
g |
yes/no |
Pa |
Knudsen-cell 1 |
0.01483 |
yes |
4.42E-02 |
0.01499 |
yes |
5.00E-02 |
0.01211 |
yes |
4.06E-02 |
Knudsen-cell 2 |
0.01377 |
yes |
4.10E-02 |
0.01394 |
yes |
4.65E-02 |
0.01127 |
yes |
3.78E-02 |
Knudsen-cell 3 |
0.01293 |
yes |
3.85E-02 |
0.01318 |
yes |
4.40E-02 |
0.01065 |
yes |
3.57E-02 |
Knudsen-cell 4 |
0.01837 |
yes |
5.48E-02 |
0.01828 |
yes |
6.10E-02 |
0.01435 |
yes |
4.81E-02 |
Mean |
|
yes |
4.46E-02 |
|
yes |
5.04E-02 |
|
yes |
4.05E-02 |
Standard deviation: |
|
|
7.13E-03 |
|
|
7.50E-03 |
|
|
5.24E-03 |
Mean of measured values: |
|
4.519E-02 |
|
|
|
|
|
|
|
Standard deviation: |
|
4.954E-03 |
RSD: |
|
11.0% |
|
|
|
Description of key information
For the test item Hatcol 3178, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.93 * 10-08Pa
Vapour pressure at 25 °C: 4.28 * 10-08Pa
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The method is based on the estimation of the mass of test item flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of effused vapour is obtained by determining the loss of mass of the cell. The vapour pressure is calculated by applying the Hertz-Knudsen relation. The recommended range is 10–10to 1 Pa.
The vapour pressure of Hatcol 3178 was determined following EU A.4 using the effusion method (weight loss).
Vapour pressure was examined at nine different temperatures. Three temperatures could be evaluated as they showed reproducible weight loss. For these temperatures, 1/T was plotted against log (P).
Vapour Pressures (Effusion Method)
Experiment |
T |
Mean P |
Stand. Dev. P |
RSD P |
No. |
K |
Pa |
Pa |
% |
7 |
393.2 |
3.65E-03 |
1.05E-03 |
28.7% |
8 |
408.2 |
1.14E-02 |
1.14E-03 |
10.0% |
9 |
423.2 |
4.52E-02 |
4.95E-03 |
11.0% |
In this table, E-0X represents multiplication with 10-X.
Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation
The graph 1/T vs. log (P) shows a straight line with a correlation coefficient of - 0.9971.
For the test item Hatcol 3178, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:
Vapour pressure at 20 °C: 1.93 * 10-08Pa
Vapour pressure at 25 °C: 4.28 * 10-08Pa
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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