Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE CATEGORY APPROACH
This read-across hypothesis is based on a category approach. Within this approach, it is assumed that, based on structural similarity, the source and target substances will display similar toxicological properties. Of the category approaches detailed in the RAAF guidance document, Scenario 6 “Difference compounds have the same type of effect(s)” is considered the most appropriate hypothesis for this read-across. This read-across is detailed in the read-across justification document provided under 'Assessment Report'.
1. HYPOTHESIS FOR THE CATEGORY APPROACH (ENDPOINT LEVEL)
Please refer to the read-across justification document.
2. CATEGORY APPROACH JUSTIFICATION (ENDPOINT LEVEL
Please refer to the read-across justification document. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOELR
- Effect conc.:
- >= 2 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Key result
- Duration:
- 21 d
- Dose descriptor:
- LOELR
- Effect conc.:
- > 2 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study planned (based on read-across)
- Justification for type of information:
- REPORTING FORMAT FOR THE CATEGORY APPROACH
This read-across hypothesis is based on a category approach. Within this approach, it is assumed that, based on structural similarity, the source and target substances will display similar toxicological properties. Of the category approaches detailed in the RAAF guidance document, Scenario 6 “Difference compounds have the same type of effect(s)” is considered the most appropriate hypothesis for this read-across. This read-across is detailed in the read-across justification document provided under 'Assessment Report'.
1. HYPOTHESIS FOR THE CATEGORY APPROACH (ENDPOINT LEVEL)
Please refer to the read-across justification document.
2. CATEGORY APPROACH JUSTIFICATION (ENDPOINT LEVEL
Please refer to the read-across justification document. - Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
Referenceopen allclose all
Description of key information
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Dose descriptor:
- NOEC
- Effect concentration:
- >= 2 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
