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EC number: 255-527-0 | CAS number: 41741-86-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
- There is a high probability that the product is not acutely harmful to fish.
- Acutely toxic to aquatic invertebrates.
- There is a high probability that the product is not acutely harmful to aquatic plants.
- The inhibition of the degradation activity of activated sludge is not anticipated when introduced to biological treatment plants in appropriate low concentrations.
Additional information
Short-term toxicity to fish
In a 96-hour acute toxicity study, zebrafish (Danio rerio) were exposed to the test item at a loading rate of 0 (control) and 100 mg/L under static conditions in accordance with the OECD 203 test guideline. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. The 96 hour LC50/ LL50was > 100 mg/L based on the loading rate of the test substance. The test substance had no observable acute effect onfishup to its saturation limit in test media and under test conditions.The results in this study are consistent with all validity criteria and the test is valid according to the guidelines of this study. No deviations from test guidelines or other incidents occurred during the course of the reported test which may have influenced the results.
Short-term toxicity to daphnia
A Klimisch 1 GLP study (BASF,
2000) was performed according to OECD guideline 202, EU method C.2, EPA
OPPTS 850.1010 and other guidelines to determine the mobilization of
Daphnia magna in an aqueous extract (eluate) of the test substance after
48 hours (observation times: at start of test, 24 and 48 hours after
start of the test). The following concentrations of the test substance
were used: 100, 50, 25, 12.5, 6.25, 3.13, 1.56, 0.78 and 0.39 mg/L
(dilution factor: 2). The effect concentrations at which 0%, 50% and
100% of the animals are immobile, were determined: EC0 (48 h) = 0.688
mg/L (nominal 6.25 mg/L); EC50 (48 h) = 2.56 mg/L (nominal 23.3 mg/L);
EC100 (48 h) = 11 mg/L (nominal >100 mg/L).
Toxicity to aquatic plants
In a 7 day growth inhibition study study,Lemna gibbawere exposed to the test item at loading rates of 0 (control), 0.032, 0.1, 0.32, 1.0 and 3.2 mg/L under static conditions in accordance with the OECD 221 guideline. The water pH and temperature were within acceptable guideline specifications. Plant growth (as frond number) and phytotoxic effects were observed on day 2, 5 and test termination.The ErL 10 based on growth rate and frond number was determined at 1.11 mg/L and 0.43 mg/L based on dry weight. The ErL50 values were > 3.2 mg/L loading rate.The results in this study are consistent with all validity criteria and the test is valid according to the guidelines of this study. No deviations from test guidelines or other incidents occurred during the course of the reported test which may have influenced the results.
Toxicity to microorganisms
A Klimisch 1 GLP (study (BASF,1999) was performed according to OECD
guideline 209 and ISO guideline 8192 to determine the inhibitory effect
of the test substance on the oxygen consumption of activated sludge
after 180 minutes of incubation time. The used concentrations were 98,
499 and 1000 mg/L of the test substance and 1, 10 and 100 mg/L of the
used reference product 3,5-dichlorophenol. The effect concentration
values for the test substance and the reference product were based on
added nominal concentrations and not on analytically determined values.
The following nominal concentrations at 20%, 50% and 80% respiration
inhibition of activated sludge were determined for the test substance:
EC20 (3 h) ca. 280 mg/L (reference product: ca. 2.1 mg/L), EC50 (3 h)
>500 mg/L (reference product: ca. 13 mg/L); EC80 (3 h) >500 mg/L
(reference product: ca. 67 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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