Registration Dossier
Registration Dossier
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EC number: 944-188-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
With regard to irritation there are no data on the pigment as such, however there are no reported incidents at the production site concerning irritation (regardless of exposure route), nor corrosive properties.
As for the important components of the pigment, there is a quite large number of studies on magnetite and hematite showing that neither of them are irritating to the skin or eye. As for sparingly soluble lead compounds, experimental studies on animals as well as a huge number of occupational studies have shown that sparingly soluble lead compounds do not exhibit irritant or corrosive properties in acute inhalation studies. There are no reports of respiratory irritation in occupationally exposed workers.
In conclusion for the pigment no skin or eye irritation observed in experimental studies conducted according to Annex V test guidelines. No evidence of respiratory irritation in rat acute toxicity studies up to 5mg/L and no reports of respiratory irritaion following extensive use of this substance in the workplace.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
