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EC number: 276-374-6 | CAS number: 72139-17-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 18, 2017 to March 09, 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 122 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 490 g/L
- Incubation duration:
- 24 h
- Temp.:
- 30 °C
- pH:
- 5.9
- Key result
- Water solubility:
- 130 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 493 g/L
- Incubation duration:
- 48 h
- Temp.:
- 30 °C
- pH:
- 6
- Key result
- Water solubility:
- 78 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 495 g/L
- Incubation duration:
- 72 h
- Temp.:
- 30 °C
- pH:
- 6.1
- Remarks on result:
- other:
- Remarks:
- It is assumed that the significantly lower value of the water solubility resulting from the 72 h experiment compared to the shorter stirred experiments (48 h and 24 h) results from a further decomposition of the test item. Therefore solely the water solubility values of the 24 h and 48 h experiment were taken into account for the final value of the water solubility.
- Details on results:
- Individual results
Preliminary test
In a stepwise procedure, increasing volumes of demineralized water were added at room temperature to a defined amount of the test item. After each addition of an amount of water the mixture was treated with ultrasound for 10 minutes and visually checked for any undissolved particles.
Table: Results of the preliminary test
Amount of test item / mg Added volume of demineralized water/ mL Total volume of demineralized water/ mL Appearance of mixture
99.2 0.1 0.1 blue precipitate
0.4 0.5 blue solution with particles
0.5 1.0 blue solution with small particles
1.0 2 clear blue solution without any particles
The preliminary test showed that the water solubility of the test item is > 10 mg/L (between 49.6 g/L and 99.2 g/L). According to the preliminary test the water solubility was determined by the flask method in the main test.
Flask method
The flask method was performed as described above. The data for the evaluation are given in Table 5. After the equilibration time precipitate was observed in the flasks of the experiments excluding in the blank experiment. The water solubility was calculated from the measured and unrounded concentration values and not from the rounded values given in Table 5.
Table 5: Water solubility experiments of the test item
Experiment 24 h experiment 48 h experiment 72 h experiment Blank experiment (72 h)
Amount of test item / g 4.90 4.93 4.95 --
Amount of demineralized water / mL 10 10 10 10
Stirring time at 30 °C / h 24 48 72 72
pH at 24 °C 5.9 6.0 6.1 5.5
Dilution factor 1000 1000 1000 1000
Measured concentration / mg/L 122.0 / 122.1 130.0 / 130.1 78.2 / 78.0 -- / --
Mean concentration / mg/L 122.1 130.1 78.1 --
Water solubility / g/L 122 130 78 --
The HPLC chromatograms given in chapter 6 showed that the samples of the water solubility experiments had two additional signals between 5.5 min and 6 min (despite of the test item signal at 6.2 min), compared to the standard solution of the test item. These additional signals which may result from a decomposition of the test item increased in the 72 h experiment, compared to the shorter stirred experiments (24h and 48 h). Therefore it is assumed that the significantly lower value of the water solubility resulting from the 72 h experiment compared to the shorter stirred experiments (48 h and 24 h) results from a further decomposition of the test item. Therefore solely the water solubility values of the 24 h and 48 h experiment were taken into account for the final value of the water solubility.
The water solubility of the test item at 20 °C was determined to be 126 g/L (± 10 g/L) without correction of the purity. - Executive summary:
Final results
The water solubility cSof the test item Reactive Blue 114 at a temperature of 20 °C was determined according to the flask method. Without correction of the purityit was found to be:
cS = 126 g/L (± 10 g/L)
Reference
Description of key information
Key value for chemical safety assessment
- Water solubility:
- 126 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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