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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From December 2016 to May 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
OECD guideline study, conducted under GLP. Test substance adequately identified. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
other: slow stir vessels
Key result
Water solubility:
>= 0 - <= 50 µg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
>= 5.35 - <= 6.29
Conclusions:
The water solubility of Koalube 136 was <0.05 μg/mL (< 50 μg/L) at 20 ± 0.5°C.
Executive summary:

This procedure conforms to those outlined in OECD Guideline 105. Preliminary investigations suggested that the water solubility was very low and that the most appropriate method for the determination of water solubility was the adoption of the slow stir method detailed in OECD guideline 123.

The test substance was not detected in any of the water solubility samples; it was therefore concluded that the water solubility was below the limit of quantitation, 0.05 μg/mL of the analytical method. The pH of the samples was 5.35 to 6.29, which reflects the pH expected of double-distilled water.

The water solubility of the test item was regarded as <0.05 μg/mL at 20 ± 0.5°C.

Description of key information

The water solubility of Koalube 136 was <0.05 μg/mL at 20 ± 0.5°C.

Key value for chemical safety assessment

Water solubility:
50 µg/L
at the temperature of:
20 °C

Additional information

The water solubility of Koalube 136 was <0.05 μg/mL at 20 ± 0.5°C.