Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes
Type of method:
gas saturation method

Test material

Constituent 1
Chemical structure
Reference substance name:
Escin
EC Number:
229-880-6
EC Name:
Escin
Cas Number:
6805-41-0
Molecular formula:
C110H172O48
IUPAC Name:
(2S,3S,4S,5R,6R)-6-{[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-9-(acetyloxy)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-[(2-methylbutanoyl)oxy]-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-hydroxy-3,5-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxane-2-carboxylic acid; (2S,3S,4S,5R,6R)-6-{[(3S,4S,4aR,6aR,6bS,8R,8aR,9R,10R,12aS,14aR,14bR)-9-(acetyloxy)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-{[(2E)-2-methylbut-2-enoyl]oxy}-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl]oxy}-4-hydroxy-3,5-bis({[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy})oxane-2-carboxylic acid
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
30 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

 Sample Type  W (g)  Vn2 (m3)  T (K)  P (Pa)
 Vapor pressure at 20°C 2.5 x 10-6   0.05711 293   9.4 x 10 -5  
  Vapor pressure at 30°C   2.5 x 10-6  

0.05809

 303  9.6 x 10-5   

Applicant's summary and conclusion

Conclusions:
The vapour pressure of Escin was then stated to be lower than 9.4 x 10 -5 Pa at 293K temperature (20°C) and lower than   9.6 x 10 -5 Pa at 303K temperature (30°C).