Registration Dossier
Registration Dossier
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EC number: 226-558-7 | CAS number: 5424-01-1
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 February 2013 - 28 March 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study has been performed in accordance with the EC A.2 and OECD 103 guidelines and complied with the principles of GLP.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- 3-aminopyrazine-2-carboxylic acid
- EC Number:
- 226-558-7
- EC Name:
- 3-aminopyrazine-2-carboxylic acid
- Cas Number:
- 5424-01-1
- Molecular formula:
- C5H5N3O2
- IUPAC Name:
- 3-aminopyrazine-2-carboxylic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- See endpoint 4.2
Constituent 1
Results and discussion
Boiling point
- Remarks on result:
- other: Boiling of the test substance was not observed below the temperature at which decomposition started.
Any other information on results incl. tables
Boiling of the test substance was not observed below the temperature at which decomposition started.
Applicant's summary and conclusion
- Conclusions:
- No boiling before decomposition was observed for Amiloride Compound 5 using differential scanning calorimetry (GLP-compliant study in accordance with EC A.2, OECD 103 and EPA OPPTS 830.7220). The substance has no boiling temperature.
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