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EC number: 211-681-0 | CAS number: 685-63-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- January 2002 - February 2002
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- lot No.of test material: 110100
- Expiration date of the lot/batch: assumed stable for the duration of the studys under the storage condition
- Purity: 99.9%
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- - Source of activated sludge: sludge of city sewage treatment plant from Kurume central treatment center (japan)
- Storage conditions: aerobic condition
- Activated sludge preparation: the sampling sludge was filtered through a filter paper and a filter was used as activated sludge. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 7.09 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: mineral medium was performed following the OECD guideline
- Test temperature: 20 +/- 1°C
- pH adjusted: /no
- Culturing apparatus: incubator (SANYO)
- Test performed in closed vessels due to significant volatility of test substance: yes
- Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (test mat. analysis)
- Value:
- 2
- Sampling time:
- 28 d
- Details on results:
- The degradation of the test item was determined both by measurement of the dissolved oxygen (DO) and by analytical monitoring of the test item.
The percentage degradation using the BOD was 0% at 28 days.
The percentage degradation using the analytical monitoring (GC) of the test item was 2 % at 28 days
details of analytical results and the percentage degradation at all time points are given in the table 1 and 2 respectively (in "any other information on results including tables" - Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test item was not biodegraded by microorganisms under the tests conditions.
- Executive summary:
The determination of the "ready" biodegradability of the test item was performed using the closed bottle test according to OECD guideline No. 301 D, 1992.
The test substance was tested at 0.709 mg/l, corresponding to theoretical amount of 5.60 mg dissolved oxygen/l.
The study consisted of 29 bottles:
- 11 control blanks (no test substance),
- 12 test bottles (Sludge + Test item),
- 4 reference solutions (Sludge + sodium benzoate)
- 2 test solution blanks (Water + Test item),
Test duration was 28 days. The relative biodegradation values calculated from both the measurements of the biologic Oxygen Demand (BOD) and the test item concentration performed during the test period revealed no significant biodegradation of the test item.
The percentage degradation using the BOD was 0% at 28 days.
The percentage degradation using the analytical monitoring (GC) of the test item was 2 % at 28 days.
Since all criteria for acceptability of the test were met, this study was considered to be valid.
The test item was not readily biodegradable by microorganisms under the tests conditions.
Reference
Table 1 : Analytical result of the test solutions
|
Water + test item |
Sludge + test item |
Theoretical amount |
|||
1 |
2 |
1 |
2 |
|
||
BOD |
mgO2/L |
- |
- |
0 |
0 |
5.60 |
Residual amount and % residue of the test item |
mg |
0.713 |
0.714 |
0.686 |
0.708 |
0.709 |
% |
101 |
101 |
97 |
100 |
- |
Table 2 : Percentage degradation
Method |
Percentage degradation % The value in () is a mean value |
|||
7 days |
14 days |
21 days |
28 days |
|
BOD |
3 |
0 |
0 |
0 |
1 |
0 |
0 |
0 |
|
(2) |
(0) |
(0) |
(0) |
|
GC |
- |
- |
- |
4 |
- |
- |
- |
1 |
|
|
|
|
(2) |
Description of key information
The Hexafluoro-1,3-butadiene was not readily biodegradable under the conditions of the closed bottle test (OECD guideline No. 301 D and GLP compliant ).
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
One reliable study is available for the Hexafluoro-1,3-butadiene for this endpoint.
The "ready" biodegrability of the test item Hexafluoro-1,3-butadiene was determined in one GLP-compliant study performed in accordance with the OECD guideline No. 301D, without deviations. The study is considered as reliable (Klimisch 1) and is selected as a key study for the endpoint.
The determination of the "ready" biodegradability of the test item was performed using the closed bottle test
The test substance was tested at 0.709 mg/l, corresponding to theoretical amount of 5.60 mg dissolved oxygen/l.
The study consisted of 29 bottles:
- 11 control blanks (no test substance),
- 12 test bottles (Sludge + Test item),
- 4 reference solutions (Sludge + sodium benzoate),
- 2 test solution blanks (Water + Test item),
Test duration was 28 days. The relative biodegradation values calculated from both the measurements of the biologic Oxygen Demand (BOD) and the test item concentration performed during the test period revealed no significant biodegradation of the test item.
The percentage degradation using the BOD was 0% at 28 days.
The percentage degradation using the analytical monitoring (GC) of the test item was 2 % at 28 days
Since all criteria for acceptability of the test were met, this study was considered to be valid.
The test item was not readily biodegradable by microorganisms under the tests conditions.
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