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Diss Factsheets
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EC number: 287-337-9 | CAS number: 85480-57-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
Skin sensitisation:
A study was conducted to determine the skin sensitisation potential of the read-across substance, benzenesulfonic acid, C10 -13 -alkyl derivs., sodium salts, according to OECD Guideline 406, in compliance with GLP. Ten male and ten female Hartley guinea pigs were included in the experiement. The induction was first done by intradermal injection. Test animals were injected with 0.1 mL Freund Complete Adjuvant (FCA), 0.1 mL of 25% test substance in water, and 0.1 mL test substance in FCA in water (final concentration 25%). Control group was treated in a similar manner with only FCA and water. On Day 7, a second, epicutaneous challenge was done. 0.5 mL of test susbtance (25%) was placed on gauze, and then placed on the animals. The animals were then bandaged, and the test substance remained in contact for 48 h. Control animals were exposed to vehicle only. The challenge consisted of 0.2 mL of 12.5 % test substance placed on gauze, which was then placed on the test and control animals. Gauze containing only vehicle was placed on the left flank. The exposure lasted 24 h. Observations for irritation were made at 24 and 48 h after the end of exposure. Skin was scored for irritation using the Draize scale. No positive reactions were observed at any of the time points. Under the study conditions, the substance was not sensitizing to guinea pig skin (RBM, 1985).
Justification for classification or non-classification
Based on the results of the an in vivo study with the read-across substance, benzenesulfonic acid, C10 -13 -alkyl derivs., sodium salts in rabbits, no classification for skin sensitisation is warranted according to EU CLP (EC) 1272/2008 criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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