1,4-diamino-2,3-dichloroanthraquinone

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Justification for type of information:

Data is from Environmental Toxicology and Chemistry journal.

Qualifier:

according to guideline

Guideline:

other: refer principle below

Principles of method if other than guideline:

The Octanol water partition coefficient of chemical 1,4-diamino-2,3-dichloroanthraquinone was determined by using slow stirring method in this method solubility of test chemical in water and Octanol was analysed by spectrophotometer.

GLP compliance:

not specified

Type of method:

slow-stirring method

Partition coefficient type:

octanol-water

Specific details on test material used for the study:

- Name of the test chemical: 1,4-diamino-2,3-dichloroanthraquinone
- Molecular formula: C14H8Cl2N2O2
- Molecular weight: 307.135 g/mol
- Smiles Notation: c1cc2c(cc1)C(=O)c1c(c(c(c(c1N)Cl)Cl)N)C2=O
- InChI: 1S/C14H8Cl2N2O2/c15-9-10(16)12(18)8-7(11(9)17)13(19)5-3-1-2-4-6(5)14(8)20/h1-4H,17-18H2
- Substance Type: Organic
- Physical State: Solid crystal powder (purple-black)

Analytical method:

other: Spectrophotometer

Key result

Type:

log Pow

Partition coefficient:

4.56

Temp.:

25 °C

Remarks on result:

other: other details not available

Conclusions:

The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone was determined to be 4.56 by using slow stirring method at 25oC.

Executive summary:

The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone (CAS no. 81-42-5) was determined by using slow stirring method at 25oC. In this method the 1 L thermostated flask was used with 800 mL water and 100 mL ocatanol then test chemical 1,4-Diamino-2,3-dichloroanthraquinone was dissolved in Octanol at concentration 0.1 g/L then required amount slowly pipette into flask. After that water samples and Octanol samples were analysed separately by using spectrophometer and both samples were extracted by using different methods. The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone was determined to be 4.56. By this value partition coefficient this chemical is condidered to be hydrophobic in nature.

Description of key information

The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone (CAS no. 81-42-5) was determined by using slow stirring method at 25oC. In this method the 1 L thermostated flask was used with 800 mL water and 100 mL ocatanol then test chemical 1,4-Diamino-2,3-dichloroanthraquinone was dissolved in Octanol at concentration 0.1 g/L then required amount slowly pipette into flask. After that water samples and Octanol samples were analysed separately by using spectrophometer and both samples were extracted by using different methods. The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone was determined to be 4.56. By this value partition coefficient this chemical is condidered to be hydrophobic in nature.

Key value for chemical safety assessment

Log Kow (Log Pow):

4.56

at the temperature of:

25 °C

Additional information

The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone (CAS no. 81-42-5) was determined by using slow stirring method at 25oC. In this method the 1 L thermostated flask was used with 800 mL water and 100 mL ocatanol then test chemical 1,4-Diamino-2,3-dichloroanthraquinone was dissolved in Octanol at concentration 0.1 g/L then required amount slowly pipette into flask. After that water samples and Octanol samples were analysed separately by using spectrophometer and both samples were extracted by using different methods. The Octanol water coefficient of test chemical 1,4-Diamino-2,3-dichloroanthraquinone was determined to be 4.56. By this value partition coefficient this chemical is condidered to be hydrophobic in nature.