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Diss Factsheets
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EC number: 701-138-0 | CAS number: 242482-67-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No acute toxicity observed in reliable studies at the nominal limit concentration of 1000 mg/L (analytically verified) for freshwater fish or up to the highest tested nominal concentration of 1000 mg/L for marine fish.
Key value for chemical safety assessment
Additional information
For the very well soluble compound 6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol a reliable acute toxicity test (reliability category 2, GLP-compliance) performed according to OECD 203 (1992) on Danio rerio clearly demonstrate that no toxicity is observed up to the tested limit concentration of 1000 mg/L. Neither at nominal 1000 mg/L nor in the control was any mortality observed during the test. No adverse effects on swimming or breathing or general behavior and no altered appearance were observed. The limit concentrations were analytically verified by DOC analysis (mean values: 852.6 mg/L.
6-(isononanoylamino)hexanoic acid is reported to be not soluble in water. Also this substance was tested on Danio rerio for acute toxicity (OECD 203, GLP compliance). At the two lower tested concentrations (220 and 500 mg/L) slight depositions at the bottom and surface of test basins were observed, while at 1000 mg/L heavy depositions and floating particulate matter were noted. Up to 500 mg/L no lethality was observed, while at 1000 mg/L all fish died. Sub-lethal effects were noted at 220 and 500 mg/L. As particulate matter is reported for all test solutions and especially at 1000 mg/L, physical interaction is most probably causal for observed effects and the otherwise well performed study is assessed as not reliable.
In addition, for 6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol a GLP-conform test on acute toxicity to salt water fish (Turbot, Scophthalmus maximus) was performed in accordance with PARCOM (1995) method and OECD 203 as a semi-static test with change of test medium after 48 hours (reliability category 2). In accordance with the above test results, up to the highest tested concentration of 1000 mg/L no mortality was observed (96 hours).
In conclusion, by read across from the similar substance 6-(isononanoylamino)hexanoic acid, compound with 2,2’,2’’-nitrilotriethanol also 6-(isononanoylamino)hexanoic acid is regarded as inherently non-toxic to fish as regards solutions free from particulate matter.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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