Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-185-0 | CAS number: 117-34-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation,the chemical diphenyl acetic acid was observed to be white colored crystalline powder in appearance.
Melting point:
The melting point determination of diphenyl acetic acid (CAS No. 117-34-0) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined to be 140.3 °C-143.5°C at 977.6hPa
Boiling point:
The boiling point determination of diphenyl acetic acid (CAS No. 117-34-0) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 248.3°C at 976.3 hPa.
Density:
The density of substance diphenyl acetic acid (CAS No. 117-34-0)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of substance diphenyl acetic acid is was determined to be 1.199 g/cm³at 20 °C and 977.5 hPa.
Particle Size Distribution:
The particle size distribution of test item diphenyl acetic acid (CAS No. 117-34-0 ) was determined by granulometric analysis with rotap sieve shaker. The particle sizedistribution was determined to be in the range of 150 micron to 25 micron.
Vapor Pressure:
Modified Grain method was used to estimate the vapour pressure of diphenylacetic acid using MPBPVP v1.43 of EPI SUITE. The estimated vapour pressure of diphenylacetic acid at 25 degC was 0.000667 Pa.
Partition Coefficient:
The partition Coefficient n-octanol/water of diphenyl acetic acid(CAS No.117-34-0) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. The reference substances were chosen according to functional group similarity with the test substance and calibration graph was prepared. The reference substances were biphenyl, cinnamic acid, 3-methylbenzoic acid, dodecanoic acid, n-butylbenzene and naphthalene having Pow value ranging from 2.1 to 4.6. TheLog Pow value was determined to be 3.1729 ± 0.0178 at 25°C.
The experimental octanol - water partition coefficient of diphenyl acetic acid was also determined using Shake – flask method. The study was performed at ambient temperature (i.e 25 deg C).The aqueous phase was analyzed using absorption spectroscopy. The experimental logKOW value for diphenyl acetic acid was determined to be 2.6 at 25 deg C.
Both the experimental values suggests that diphenyl acetic acid is hydrophillic in nature which is also supported by its solubility in water.
Water Solubility:
The water solubility determination of test item diphenyl acetic acid (CAS No. 117-34-0) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of diphenyl acetic acid (CAS: 117-34-0) in water was determined to be 873.0825 mg/l at 29°C.
Data from various authoritative databases suggests that the experimental solubility of diphenyl acetic acid in water at 25 deg C was 127 mg/l.
The experimental values indicates that diphenyl acetic acid is soluble in water.
Surface tension:
From predicted ACD lab data, the surface tension of Diphenylacetic acid (117-34-0) was predicted to be 49.1 ± 3.0 dyne/cm.
Flash point:
The flash point determination of diphenyl acetic acid (CAS No. 117-34-0)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determined to be 195.3°C at 976.4hPa.Based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence thediphenyl acetic acid (CAS No. 117-34-0)was considered to be non-flammable.
Autoflammability:
The substance is a solid having melting point 140.3-143.5 degree C which is less than or equal to 160 deg C. Hence the auto-iginition endpoint was considered for waiver.
Flammability:
Diphenylacetic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that Diphenylacetic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus Diphenylacetic acid was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
pH:
The pH determination of test item diphenyl acetic acid (CAS No 117-34-0) was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of pH meter and it was observed to be 3.72at 28 °C. Based on the value, diphenyl acetic acid (CAS No 117-34-0) was considered to be acidic in nature.
Viscosity:
The study does not need to be conducted because the substance is a solid
Additional information
Appearance:
On the basis of physical observation,the chemical diphenyl acetic acid was observed to be white colored crystalline powder in appearance.
Other supporting studies from reliable sources such as authoritative database and handbook,the chemical diphenyl acetic acid was observed to be white colored crystals in appearance or needles form from water and small plates from alchohol.
Melting point:
The melting point determination of diphenyl acetic acid (CAS No. 117-34-0) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determined to be 140.3 °C-143.5°C at 977.6hPa
Other supporting studies from various reliable sources such as authoritative database and handbook,the melting point of chemical diphenyl acetic acid was determined to be in the range of 147 degree C to 149 degree C.
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of melting point temperature as 140.3 degree C to 143.5 degree C, thus considered as key study for the c-hemical safety assessment.
Boiling point:
The boiling point determination of diphenyl acetic acid (CAS No. 117-34-0) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determined to be 248.3°C at 976.3 hPa.
Other supporting study from authoritative database,the boiling point of chemical diphenyl acetic acid was determined to be 114 degree C at 0.05 torr pressure,
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of boiling point temperature as 248.3 degree C thus considered as key study for the chemical safety assessment.
Density:
The density of substance diphenyl acetic acid (CAS No. 117-34-0)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer. The mean density of substance diphenyl acetic acid is was determined to be 1.199 g/cm³at 20 °C and 977.5 hPa.
Other supporting studies from various reliable sources such as handbook and prediction databases,the density of chemical was determined to be 1.257 g/cm3 at 15 degree C (experimental data) and 1.174 ± 0.06 g/cm3 at 20 degree C(predicted data).
As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 1.199 g/cm3 at 20 degree C, thus considered as key study for the chemical safety assessment.
Particle Size Distribution:
The particle size distribution of test item diphenyl acetic acid (CAS No. 117-34-0 ) was determined by granulometric analysis with rotap sieve shaker. The particle sizedistribution was determined to be in the range of 150 micron to 25 micron.
Vapor Pressure:
Modified Grain method was used to estimate the vapour pressure of diphenylacetic acid using MPBPVP v1.43 of EPI SUITE. The estimated vapour pressure of diphenylacetic acid at 25 degC was 0.000667 Pa.
Partition Coefficient:
The partition Coefficient n-octanol/water of diphenyl acetic acid(CAS No.117-34-0) was determined by the Reverse Phase High Performance Liquid Chromatographic method according to OECD Guideline No. 117 for testing of Chemicals. The reference substances were chosen according to functional group similarity with the test substance and calibration graph was prepared. The reference substances were biphenyl, cinnamic acid, 3-methylbenzoic acid, dodecanoic acid, n-butylbenzene and naphthalene having Pow value ranging from 2.1 to 4.6. TheLog Pow value was determined to be 3.1729 ± 0.0178 at 25°C.
The experimental octanol - water partition coefficient of diphenyl acetic acid was also determined using Shake – flask method. The study was performed at ambient temperature (i.e 25 deg C).The aqueous phase was analyzed using absorption spectroscopy. The experimental logKOW value for diphenyl acetic acid was determined to be 2.6 at 25 deg C.
Both the experimental values suggests that diphenyl acetic acid is hydrophillic in nature which is also supported by its solubility in water.
Water Solubility:
The water solubility determination of test item diphenyl acetic acid (CAS No. 117-34-0) was done as per the OECD guideline 105 and by spectrophotometric analytical method as per OECD 101. The solubility of diphenyl acetic acid (CAS: 117-34-0) in water was determined to be 873.0825 mg/l at 29°C.
Data from various authoritative databases suggests that the experimental solubility of diphenyl acetic acid in water at 25 deg C was 127 mg/l.
The experimental values indicates that diphenyl acetic acid is soluble in water.
Surface tension:
From predicted ACD lab data, the surface tension of Diphenylacetic acid (117-34-0) was predicted to be 49.1 ± 3.0 dyne/cm.
Flash point:
The flash point determination of diphenyl acetic acid (CAS No. 117-34-0)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determined to be 195.3°C at 976.4hPa.Based on criteria mentioned in CLP regulation the chemical has flash point >than 60 degree C hence thediphenyl acetic acid (CAS No. 117-34-0)was considered to be non-flammable.
Autoflammability:
The substance is a solid having melting point 140.3-143.5 degree C which is less than or equal to 160 deg C. Hence the auto-iginition endpoint was considered for waiver.
Flammability:
Diphenylacetic acid does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that Diphenylacetic acid is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus Diphenylacetic acid was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.
Oxidising properties:
The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with oxidising properties and hence, the classification procedure does not need to be applied
pH:
The pH determination of test item diphenyl acetic acid (CAS No 117-34-0) was done following OECD guideline 122. pH of 1% w/v dispersion was measured with the help of pH meter and it was observed to be 3.72at 28 °C. Based on the value, diphenyl acetic acid (CAS No 117-34-0) was considered to be acidic in nature.
Viscosity:
The study does not need to be conducted because the substance is a solid
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.