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EC number: 272-812-5 | CAS number: 68915-39-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study with acceptable restrictions
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 987
- Report date:
- 1987
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: German Industrial Standard DIN 38412 part 15
- GLP compliance:
- no
Test material
- Reference substance name:
- sodium carboxylate solution
- IUPAC Name:
- sodium carboxylate solution
- Details on test material:
- - name: Sodium carboxylate solution
- purity: not specified
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Leuciscus idus
- Details on test organisms:
- - Test fish: Leuciscus idus (golden variety)
- Supplier: Fischzucht Paul Eggers, 2354 Hohenweststedt, Germany
- Body length: 5.8 cm (range 5.1 - 6.4 cm)
- Body weight: 2.4 g (range 1.8 - 3.3 g)
- Loading rate (g fish/l test water): 2.4
- Medical treatment: twice with 0.05 mg/l malachite green chloride, once with 10 mg/l tetracycline hydrochloride
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 20 - 21 °C
- pH:
- 7.6 - 10.0
- Dissolved oxygen:
- 7.5 - 8.7 mg/l
- Details on test conditions:
- - Dilution water source: reconstituted freshwater according to DIN 38412, Part II, 1982
Dilution water chemistry
- Total hardness: 2.5 mmol/l
- Acid capacity: 0.8 mmol/l
- Ratio Ca/Mg ions: 4:1
- Ratio Na/K ions: 10:1
- pH: about 7.7
- The test solution was prepared by adding the test item to the test media without any pre-treatment. Then, the fish were placed into the test aquaria. Nominal test concentrations: 5000 and 10000 mg/l. In addition, a control was tested in parallel.
- Test vessels: All glass aquaria (30 x 22 x 24 cm)
- Volume of water: 10 l
- Continuous aeration with oil-free air, slight
- Photoperiod: 16 : 8 hours day-night regime
- One test vessel per treatment
- No of animals per test concentration and control: 10
- Duration of adaption: about 2 weeks
- Mortality during the adaption period: 0 %
- Withdrawal of food: 1 day before and during exposure.
- observations: mortality and symptoms after 0, 4, 24, 48, 72, and 96 h
- measurements: pH and oxygen content after 0, 24, 48, 72 and 96 h
- Statistical methods: The median lethal concentration (LC50) was calculated using Probit Analysis (Finney D.J., Probit Analysis, Cambr. Univ. Press, 3rd Edition, 1971)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- > 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 10 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Any other information on results incl. tables
- Sublethal observations / clinical signs:
- RS-Freetext:
No analytical dose-verification of the test item was carried out.
LC 50 (48h): > 10000 mg/l
LC 50 (72h): > 10000 mg/l
LC 50 (96h): > 10000 mg/l
Table showing cumulative mortality:
Cumulative mortality
Nom. conc. (mg/l) 1h 4h 24h 48h 72h 96h
Control 0 0 0 0 0 0
5000 0 0 0 0 0 0
10000 0 0 0 0 0 0
No symptoms observed
Reference substances (if used):
48 h-LC50 of the positive control Chloroacetamide: about 32 mg/l (corresponds to normal sensitivity).
Behavior of the test item during the test:
No remarkable observations.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.