Potassium titanium oxide (K1.88-2.13Ti8O16.94-17.07)

Toxicity to soil microorganisms

Administrative data

Endpoint:

toxicity to soil microorganisms

Type of information:

other: statement

Adequacy of study:

key study

Study period:

July 2019

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Cross-reference

Cross-reference 1

Reason / purpose for cross-reference:

reference to other study

Reference

Terracess TF is an inorganic substance with very low water solubility. No adverse effects were found, other than effects in the aquatic tests at levels far above the water solubility of the test substance for two similar substances. All data available show a very low toxicity of the substance.

Toxicity to fish: The 96h-LC50 for fish exceeded the maximum solubility of the test substance in water at a loading rate of 100 mg/L. Therefore the weight of evidence shows that Terracess TF will not be toxic to fish.

Toxicity to aquatic invertebrates: The 48 hr EC50 for Daphnia magna exceeds the maximum solubility of the substance in water in studies on two similar substances. Therefore the weight of evidence shows that Terracess TF will not be toxic to Daphnia magna.

Toxicity to algae: Under the conditions of the present study with Selenastrum capricornutum exposed to TERRACESS L, the ErC50 was calculated to be above water solubility.

Toxicity to microorganisms: Under the conditions of test, Terracess L is not toxic to waste water (activated sludge) bacteria at a nominal concentration of 100 mg/L. The EC50 exceeded a loading rate of 100 mg/L.

All data available show a very low toxicity of Terracess TF.

Note: read across of Terracess L and Terracess P to Terracess TF for aquatic toxicity was accepted under NONS by the UK Environment Agency on 8th June 2005 (see the read across justification document for Ecotoxicity, section 13) on the basis that all three substances are inorganic oxides of titanium with a macromolecular structure rendering them insoluble and stable: Terracess TF: potassium titanium oxide, Terracess L: potassium lithium titanium oxide, Terracess P: potassium magnesium titanium oxide.

Cross-reference 2

Reason / purpose for cross-reference:

reference to other study

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 November 2005 to 25 January 2006

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study conducted under GLP in accordance with an internationally recognised test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

GLP compliance:

yes

Type of method:

effusion method: vapour pressure balance

Temp.:

25 °C

Vapour pressure:

ca. 0 Pa

Remarks on result:

other: First vapour pressure

Conclusions:

The vapour pressure was determined to be approximately 0.00001 Pa at 25°C

Cross-reference 3

Reason / purpose for cross-reference:

reference to other study

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

4 May to 8 June 2005

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

GLP compliance:

yes

Type of method:

column elution method

Water solubility:

< 0.02 mg/L

Temp.:

20 °C

pH:

ca. 7

Details on results:

Test substance was not detected in any of the test solutions.

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

2019

Report date:

2019

Materials and methods

Test guideline

Qualifier:

no guideline followed

Principles of method if other than guideline:

Argumentation is provided for 'study scientifically not necessary / other information available', based on available physico-chemical, fate and ecotoxicological properties information and in agreement with column 2 of Regulation (EC) No 1907/2006 Annex IX section 9.4. Effects on terrestrial organsims.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

-

EC Number:

470-870-8

EC Name:

-

Cas Number:

690271-93-3

Molecular formula:

Hill formula: K1.88-2.13 O16.94-17.07 Ti8 CAS formula: K1.88-2.13 O16.94-17.07 Ti8

IUPAC Name:

Potassium Titanium Oxide

Test material form:

solid

Details on test material:

Identification: Terracess TF
Chemical name: Potassium Titanium Oxide
Purity: 99.5% (w/w)
Physical description: white odourless powder

Sampling and analysis

Analytical monitoring:

not required

Test substrate

Details on preparation and application of test substrate:

not applicable - no test performed

Test organisms

Test organisms (inoculum):

soil

Study design

Remarks:

statement based on available physico-chemical, fate and ecotoxicological property information

Test conditions

Details on test conditions:

not applicable - no test performed

Results and discussion

Effect concentrations

Key result

Remarks on result:

not measured/tested

Details on results:

Considering the physico-chemical properties (stable inorganic compound with low water solubility) and ecotoxicological properties (acute toxicity for aquatic organisms above the water solubility limit) no significant risk to terrestrial organisms is expected. The substance has a low toxicity to aquatic micro-organisms (EC50> 100 mg/L).
The high molecular weight of the substance, its lack of solubility both in the water and octanol phase suggest that it will not be biologically available nor bioaccumulate and thus not expected to exert toxicity to soil microorganisms.

Applicant's summary and conclusion

Conclusions:

Taking into account the available information of the substance with regard to environmental relevance and exposure of the soil compartment, it is considered scientifically justified to waive testing of this substance for toxicity to soil microorganisms.