Registration Dossier
Registration Dossier
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EC number: 701-052-3 | CAS number: 146987-98-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72 h ErC10 = 0.1 mg/L, 72 h ErC50 = 0.36 mg/L (nominal) (Scenedesmus subspicatus), OECD TG 201, static, no data on GLP, RL2; read-across: Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl]
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.36 mg/L
- EC10 or NOEC for freshwater algae:
- 0.1 mg/L
Additional information
For the assessment of the toxicity of Amides, C8-18, C18 unsatd, N-[3-(dimethylamino)propyl] to freshwater algae a study conducted with the closely related source substance Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl] is available. A justification for read-across is given in IUCLID section 13.
In a 72 hour toxicity study conducted according to OECD Guideline 201, the cultures of Scenedesmus subspicatus were exposed to Amides, C8-18 even numbered, N-[3-(dimethylamino)propyl] at nominal concentrations of 0 (control), 0.025, 0.05, 0.075, 0.1, 0.25, 0.5 and 0.75 mg/L under static conditions.
The test meets validity criteria of the guideline. No analytical monitoring was made. Therefore the test results are based on nominal concentration.
ErC50 (72 h) = 0.36 mg/L
ErC10 (72 h) = 0.1 mg/L
EbC50 (72 h) = 0.18 mg/L
EbC10 (72 h) = 0.05 mg/L
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