Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 604-244-4 | CAS number: 141645-16-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
DESCRIPTION OF FIRST AID MEASURES
Inhalation:
Move exposed subject to fresh air. If not breathing, give artificial respiration (AR). If breathing is laboured, administer oxygen. Get medical attention if symptoms occur.
Skin contact:
Remove contaminated clothing/shoes. Wash exposed skin with soap and water. Get medical attention if symptoms occur.
Eye contact:
If easy to do, remove contact lenses if worn. Immediately flush eyes with copious quantities of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical attention.
Ingestion:
If swallowed, wash out mouth with water. Never give anything by mouth to an unconscious person. Get medical attention if symptoms occur.
MOST IMPORTANT SYMPTOMS AND EFFECTS, BOTH ACUTE AND DELAYED
As a pharmaceutical intermediate, the toxicity and potency of this substance are not fully known.
INDICATION OF ANY IMMEDIATE MEDICAL ATTENTION AND SPECIAL TREATMENT NEEDED
Treat symptomatically and supportively.
Fire-fighting measures
EXTINGUISHING MEDIA
• Suitable extinguishing media:
Use water spray, foam, dry powder or carbon dioxide as appropriate for surrounding fire and materials.
• Unsuitable extinguishing media:
No limitations given for this substance.
SPECIAL HAZARDS ARISING FROM THE SUBSTANCE OR MIXTURE
Combustible, but not flammable. In case of fire toxic fumes of carbon monoxide and nitrogen oxides may be emitted.
No explosivity or flammability data identified. In general, high concentrations of finely divided airborne organic particles can potentially explode if ignited.
ADVICE FOR FIREFIGHTERS
In case of fire in the surroundings: use the appropriate extinguishing agent. Wear full protective clothing and an approved, positive pressure, self-contained breathing apparatus. Decontaminate all equipment after use.
Accidental release measures
PERSONAL PRECAUTIONS, PROTECTIVE EQUIPMENT AND EMERGENCY PROCEDURES
Use recommended personal protective equipment during removal of spillages.
ENVIRONMENTAL PRECAUTIONS
Do not let the substance enter into drains. Avoid release to the environment.
METHODS AND MATERIAL FOR CONTAINMENT AND CLEANING UP
Moisten the powder spill with water prior to sweeping up. Keep in closed container and hold for waste disposal. Ventilate area and wash spill site with water after the pickup is completed.
Handling and storage
PRECAUTIONS FOR SAFE HANDLING
Avoid breathing dust and contact with eyes and skin. Handle in well-ventilated areas. Use recommended personal protective equipment. Wash thoroughly after handling.
CONDITIONS FOR SAFE STORAGE, INCLUDING ANY INCOMPATIBILITIES
Store at regular indoor conditions, generally 15-25°C. Keep container tightly closed.
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (SR28043)
- Labels:
- 9+N
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (SR28043)
- Labels:
- 9+N
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (SR28043)
- Labels:
- 9+N
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (SR28043)
- Labels:
- 9+N
Remarksopen allclose all
SpecialProvisionsopen allclose all
Exposure controls / personal protection
CONTROL PARAMETERS
To the best of our knowledge, established occupational exposure limit value is not available.
EXPOSURE CONTROL
- Appropriate engineering controls
The substance is considered to be a Category 1 of 4 (OEL >500 microgram/m3, low to intermediate toxicity) compound based on its chemical structure, toxicological assessment and use as an intermediate. The objective containment, controls and work practices should be to contain worker breathing zone concentrations to below OEL for each task or operation. In general, Category 1 handling practices, some of which are described in general in this Section, are capable of achieving the OEL. However, verification of the acceptability of these Category 1 recommended controls and work practices to meet the OEL through industrial hygiene monitoring of tasks or operations is recommended.
Selection and use of containment devices and personal protective equipment should be based on a risk assessment of exposure potential. Use local exhaust and/or enclosure at dust-generating points. High-energy operations such as milling, particle sizing, spraying or fluidizing is recommended to be done within an approved emission control or containment system.
- Personal protective equipment
Eye face protection: Wear safety glasses with side shields. An emergency eyewash station should be available.
Skin protection: Wear appropriate gloves, lab coat, or other protective overgarment if skin contact is likely. Base the choice of skin protection on the job activity, potential for skin contact and solvents and reagents in use.
Protective clothing: Use impervious clothing to prevent skin contact. The type should be selected according to concentrations, quantities and duration of handling at the specific workplace. In dust generating operation use disposable coverall.
Respiratory protection: Required when dusts are generated. Choice of respiratory protection should be appropriate to the task and the level of existing engineering controls. Use air-purifying respirator with combination filters for routine powder handling in process scale and positive-pressure air-supplied respirator if there is a potential of uncontrolled release. In the laboratory, use fume hood or laminar flow booth.
- Environmental exposure controls
Avoid release to the environment.
- Other protective measures
Wash hands in the event of contact with this substance, especially before eating, drinking and smoking. Protective equipment is not to be worn outside the work area (e.g. in common areas or out-of-doors). Decontaminate all protective equipment following use.
Stability and reactivity
REACTIVITY
No known reactivity hazards under normal conditions.
CHEMICAL STABILITY
The substance is chemically stable at standard room temperature conditions, generally 15 to 25°C.
POSSIBILITY OF HAZARDOUS REACTIONS AND CONDITIONS TO AVOID
None known.
INCOMPATIBLE MATERIALS
Oxidants. Strong acids and bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Carbon monoxide (CO) and nitrogen oxides (NOx).
Disposal considerations
WASTE TREATMENT METHODS
Dispose of wastes in accordance to prescribed national, federal, state and local guidelines, e.g. appropriately permitted chemical waste incinerator.
INFORMATION ON RECYCLING AND METHODS OF DISPOSAL FOR INDUSTRY
Avoid dust generation and inhalation of dust. Avoid contact with eyes, skin and other mucous membranes. Do not ingest. Wear all recommended personal protective equipment. Wash thoroughly after handling. Dispose waste at authorized plant, in accordance with applicable national, federal, state or local legislation. Disposal could be sent for external waste handling company for incineration. Do not empty into drains or water courses.
INFORMATION ON RECYCLING AND METHODS OF DISPOSAL FOR THE PUBLICE
This substance is not for public use.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.