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EC number: 802-122-7 | CAS number: 4494-16-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96 h) > 100 mg/L for Cyprinus carpio (OECD 203), read-across with analogue substance (Z)-9-Octadecen-1,18-dioic acid (CAS 20701-68-2)
Key value for chemical safety assessment
Additional information
Since no studies investigating the short-term toxicity of octadec-9-enedioic acid (EC 802-22-7) to fish are available, in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5 a read-across to the structurally related source substance (Z)-9-Octadecen-1,18-dioic acid (CAS 20701-68-2) was conducted. The source substance is representative to evaluate the short-term toxicity of octadec-9-enedioic acid (EC 802-22-7) to fish.
Based on their chemical structure, both the target substance (Octadec-9-enedioic acid, EC 802-22-7) and the source substance ((Z)-9-Octadecen-1,18-dioic acid, CAS 20701-68-2), belong to the family of linear monounsaturated dicarboxylic acids. While the target substance contains a cis- and trans-isomer, the source substance consists of the cis-isomer.
This read-across is justified in detail in the overall summary (IUCLID Section 6.1) and within the analogue justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment.
A GLP study according to OECD guideline 203 on the acute toxicity to carp (Cyprinus carpio) was performed with the analogue substance (Z)-9-Octadecen-1,18-dioic acid (CAS 20701-68-2), the cis-isomer of both of the stereo-isomers, under static conditions (Bogers, 2001a).
Carp were exposed to the nominal concentration of 100 mg/L and an untreated control for 96 hours. The test solution was prepared by dissolving the test item in test medium followed by 4 hrs of stirring and filtering. Also unfiltered solutions were tested. No additional solvent was used. The test water was aerated during the 3rd and 4th day of testing.
Analytical monitoring of the test item concentrations during the test were not conducted. All effect concentrations were based on nominal test concentrations. No mortality or visible effects were observed during the test period. The LC50 for filtered and unfiltered test solutions was determined to be > 100 mg/L.
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