Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 473-780-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 14 Augustus to 18 September 2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, GLP compliant; no restrictions, fully adequate for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Deviations:
- yes
- Principles of method if other than guideline:
- The method guideline states that the measurement of adsorption coefficient should be carried out on substances in their ionised and unionised forms. However, the dissociation constants of certain functional groups found in the test material made it impossible to satisfy these criteria. Testing would be required at approximately greater than pH 12 for the basic functional groups. As pH 12 or above is outside the environmental pH range for this test and also experimentally impractical, testing was carried out at approximately neutral pH with the test material unionised.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
Test material
Constituent 1
- Radiolabelling:
- no
Study design
- Test temperature:
- 30ºC (column temperature)
HPLC method
- Details on study design: HPLC method:
- EQUIPMENT
- Apparatus: HPLC
- Type: Agilent Technologies 100, incorporating autosampler and workstation
- Type, material and dimension of analytical (guard) column: Phenosphere CN 5µ (250 x 4.6 mm id)
- Detection system: UV detector
MOBILE PHASES
- Type: acetonitrile:reverse osmosis water (55:45 v/v)
- pH: 7.5
- Solutes for dissolving test and reference substances: Test material was dissolved in acetonitril, reference substances were dissolved in methanol.
DETERMINATION OF DEAD TIME
- Method: by measuring retention time of formamide
REFERENCE SUBSTANCES
- Identity: Acetanilide, phenol, atrazine, isoproturon, triadimenol, linuron, naphthalene, endosulfan-diol, α-endosulfan, phenanthrene, diclofop-methyl, DDT.
DETERMINATION OF RETENTION TIMES
- Quantity of test substance introduced in the column: 0.0025 g diluted to 100 ml with acetonitrile
- Quantity of reference substances: between 99 and 111 mg/l
REPETITIONS
- Number of determinations: Two
Results and discussion
Adsorption coefficientopen allclose all
- Type:
- Koc
- Value:
- 36 800
- Type:
- log Koc
- Value:
- 4.57
Results: HPLC method
- Details on results (HPLC method):
- See tables 12 and 13
Any other information on results incl. tables
Table 12 - Reference standards
Standard |
Retention time (min) |
Capacity factor (k) |
Log k |
Log koc |
Acetanilide |
3.536 |
0.169 |
-0.772 |
1.25 |
Phenol |
3.509 |
0.160 |
-0.796 |
1.32 |
Atrazine |
3.748 |
0.239 |
-0.621 |
1.81 |
Isoproturon |
3.898 |
0.289 |
-0.540 |
1.86 |
Triadimenol |
3.932 |
0.300 |
-0.523 |
2.40 |
Linuron |
4.05 |
0.341 |
-0.468 |
2.59 |
Naphthalene |
4.299 |
0.421 |
-0.375 |
2.75 |
Endosulfan-diol |
4.016 |
0.328 |
-0.484 |
3.02 |
α-endosulfan |
5.376 |
0.777 |
-0.109 |
4.09 |
Phenanthrene |
4.829 |
0.597 |
-0.224 |
4.09 |
Diclofop-methyl |
5.108 |
0.689 |
-0.162 |
4.20 |
DDT |
7.078 |
1.34 |
0.128 |
5.63 |
Table 13 - Sample
Injection |
Retention time (min) |
Capacity factor (k) |
Log k |
Log koc |
1 |
5.540 |
0.832 |
-0.08 |
4.56 |
2 |
5.543 |
0.833 |
-0.079 |
4.57 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Although ECHA is providing a lot of online material in your language, part of this page is only in English. More about ECHA’s multilingual practice.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
the-echa-website-uses-cookies
find-out-more-on how-we-use-cookies