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EC number: 203-008-4 | CAS number: 102-16-9
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Biodegradability of Benzyl phenylacetate (CAS no. 102 -16 -9) is predicted using OECD QSAR toolbox version 3.3 with logKow as the primary descriptor (2017). Test substance undergoes 21.83% degradation by BOD in 28 days.Thus, based on percentage degradation, the test chemical Benzyl phenylacetate was estimated to be inherently biodegradable in water.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Benzyl phenylacetate (CAS No. 102 -16 -9). If released in to the environment, 22.8% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Benzyl phenylacetate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Benzyl phenylacetate in sediment is estimated to be 135 days (3240 hrs). Based on this half-life value, it indicates that Benzyl phenylacetate is persistent in sediment.
Biodegradation in soil
The half-life period of Benzyl phenylacetate (CAS No.102 -16 -9) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 72.4% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Benzyl phenylacetate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of Benzyl phenylacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Additional information
Biodegradation in water
Predicted data for the test compound Benzyl phenylacetate (CAS no. 102-16-9) and the experimental study forits closest structurally similar read across substance with logKow as the primary descriptorwere reviewed for the biodegradation end point which are summarized as below:
In a prediction done by SSS (2017) using QSAR toolbox version 3.3 with logKow as the primary descriptor, percentage biodegradability of test chemical Benzyl phenylacetate (CAS no. 102-16-9) was estimated.Test substance undergoes 21.83% degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical Benzyl phenylacetate was estimated to be inherently biodegradable in water.
In a supporting weight of evidence study (UERL study report, Sustainability Support Services (Europe) AB, 2015) of read across substance Phenethyl Phenylacetate (CAS no. 102-20-5), 28-days Manometric respirometry test following the OECD guideline 301F to determine consumption of oxygen (O2) and thereby % degradation during the test period was conducted for evaluating the biodegradability of read across substance Phenethyl Phenylacetate. The test system included control, test substance and reference substance. The concentration of test and reference substance (sodium acetate) chosen for the study were 100 mg/l & 100 mg/l, respectively while that of inoculum was 10 ml/l. ThOD (Theoretical oxygen demand) of test and reference substance was determined by calculation. % Degradation was calculated using the values of BOD and ThOD for test substance and reference substance. The BOD28 value of Phenethyl Phenylacetate (CAS No.102-20-5) was observed to be 0.814 mgO2/mg. ThOD was calculated as 2.53 mgO2/mg. Accordingly, the % degradation of the test substance after 28 days of incubation at 20 ± 1°C according to manometric respirometry test was determined to be 32.17 %. Based on the results, the test substance, under the test conditions, was considered to be inherently biodegradable at 20 ± 1°C over a period of 28 days.
On the basis of above results for target chemicalBenzyl phenylacetate (from OECD QSAR toolbox version 3.3, 2017) and for its read across substance (UERL study report, Sustainability Support Services (Europe) AB, 2015), it can be concluded that the test substance Benzyl phenylacetate can be expected to beinherentlybiodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Benzyl phenylacetate (CAS No. 102 -16 -9). If released in to the environment, 22.8% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Benzyl phenylacetate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Benzyl phenylacetate in sediment is estimated to be 135 days (3240 hrs). Based on this half-life value, it indicates that Benzyl phenylacetate is persistent in sediment.
Biodegradation in soil
The half-life period of Benzyl phenylacetate (CAS No.102 -16 -9) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 72.4% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Benzyl phenylacetate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of Benzyl phenylacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
On the basis of available information, the test substance Benzyl phenylacetate can be considered to be inherently biodegradablein nature.
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