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Diss Factsheets
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EC number: 812-739-3 | CAS number: 157357-30-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EU Method C.2, OECD Guideline 202, GLP, key study, validity 2:
48h-EC50 = 18 mg/L (95% CI: 10-32 mg/L).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 18 mg/L
Additional information
One key study is available to assess the 48h acute toxicity of the registered substance to Daphnia magna, under static conditions, according to the EU Method C.2 and the OECD Guideline 202 with GLP statement.
The nominal test substance concentrations tested were 0.32, 1.0, 3.2, 10, 32 and 100 mg/L. Additionally, a control group was tested in parallel. Since the test substance was determined to be volatile, the test was performed in 50 mL glass tubes completely filled with about 50 mL of test medium. The test tubes were made tight with glass stoppers to avoid losses of the volatile substance.
At the start and end of the test, the analytically determined concentrations of the test substance in the test media were between 93 and 142% of the nominal values. Thus, the correct dosing of the test substance was confirmed. Furthermore, it has been demonstrated that the test substance was stable during the test period of 48 hours under the conditions of the test, and the reported biological results are based on the nominal concentrations of the test substance.
All validity criteria were fulfilled but the separation factor between concentrations greatly exceeded the guideline recommendation and no effect and 100% effect concentrations were adjacent. The 48h-EC50 value was determined as a geometric mean value of the two consecutive test concentrations with 0 and 100% inhibition of mobility, at 18 mg/L (95% confidence interval: 10 -32 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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