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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard OECD test guidelines.
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Key result
Water solubility:
186 394.274 mg/L
Conc. based on:
test mat.
Temp.:
30 °C
Remarks on result:
other: Highly soluble
Details on results:
Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:
Mean water solubility value for 48 hour run sample + 72 hour run sample
=(190106.8906+182681.6563)/2
=186394.2735 mg/L

Sample stirring

Concentration obtained on

the basis of standard curve

Dilution factor

Solubility value obtained

(mg/L)

24 hour

-

-

-

48 hour

190106.8906 mg/L

-

190106.8906 mg/L

72 hour

182681.6563 mg/L

-

182681.6563 mg/L

 

Considering the water solubility for 48 hrs and 72 hrs the mean water solubility was calculated as follows:

Mean water solubility value for 48 hour run sample + 72 hour run sample

=(190106.8906+182681.6563)/2

=186394.2735 mg/L

Conclusions:
The water solubility determination of test chemical was done as per the OECD guideline 105 and by spectro photometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 186394.2735 mg/L at 30°C. Thus, it can be concluded that test chemical is highly soluble in water.
Executive summary:

The water solubility determination of test chemical was done as per the OECD guideline 105 and by spectro photometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 186394.2735 mg/L at 30°C. Thus, it can be concluded that test chemical is highly soluble in water.

Description of key information

The water solubility determination of test chemical was done as per the OECD guideline 105 and by spectro photometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 186394.2735 mg/L at 30°C. Thus, it can be concluded that test chemical is highly soluble in water.

Key value for chemical safety assessment

Water solubility:
186 394.274 mg/L
at the temperature of:
30 °C

Additional information

The water solubility determination of test chemical was done as per the OECD guideline 105 and by spectro photometric analytical method as per OECD 101. The solubility of test chemical in water was determined to be 186394.2735 mg/L at 30°C. Thus, it can be concluded that test chemical is highly soluble in water.

Based on the data from other supporting studies from various reliable sources such as handbook and authoritative database, the test chemial was found to be highly soluble ( 150000 mg/L) in water. Thus, for the purpose of chemical safety assessment we will consider the key study value which is reported as 186394.2735 at 30 deg C, also indicating that the substance is highly soluble in water.