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Diss Factsheets
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EC number: 201-730-4 | CAS number: 87-20-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1978-07-01 to 1978-08-4
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- Principles of method if other than guideline:
- The test was conducted in accordance with "biodegradation test of chemical substance by microorganisms ect. stipulated in the Order Prescribing the items of the Test Relating to the New Chemical Substance (1974, Order of the Prime Minister, the Minster of Health and Welfare, the Minister of International Trade and Industry No.1). This guideline corresponds to 301C, Ready biodegradability: Modified MITI test or OECD 302C, Inherent Biodegradability: Modified MITI test, stipulated in the OECD Guidelines for testing of chemicals (May 12, 1981).
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Remarks:
- prefiltered open air was used for aeration
- Inoculum or test system:
- activated sludge, adapted
- Details on inoculum:
- - Preparation of activated sludge: 5L filtrated supernatant of activated sludge was mixed with 500 mL filtrated supernatant of newly collected sludge and cultured at pH 7.0 +- 1.0 and sufficient aeration (prefiltered open air = aeration)
- Source of inoculum/activated sludge: 10 places in Japan: Fukogawa city sewage plant; Fukashiba industry sewage plant, Nakahama city sewage plant; Ochiai city sewage plant, Kitakami river; Shinano river, Yoshino river, Lake Biwa, Hiroshima bay, Dookai bay.
- Method of cultivation: 30 minutes after ceasing aeration to the sludge mixture, supernatant was removed. Equal volume of dechlorination water is added and aerated again, followed by addition of synthetic sewage. This procedure was repeated once every day. The culturing was carried out at 25°C +- 2°C.
- Water filtered: yes - Duration of test (contact time):
- >= 14 - <= 28 d
- Initial conc.:
- ca. 100 mg/L
- Based on:
- test mat.
- Initial conc.:
- ca. 30 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- test mat. analysis
- Remarks:
- the test substance in the test solutions were determined
- Parameter followed for biodegradation estimation:
- DOC removal
- Remarks:
- the total organic carbon were determined
- Details on study design:
- TEST CONDITIONS
- Test temperature: 25°C +- 1°C
- pH: 7.0
- pH adjusted: yes
- Cultivating duration: 14 or 28 days
- Aeration of dilution water:
- Continuous darkness: no
TEST SYSTEM
a) Water + test substance: test vessel containing 100 mg/L test item, 2 replicates
b) Sludge + test substance: test vessel containing 100 mg/L test item + 30 mg/L sludge, 2 replicates
c) Sludge + aniline (reference substance): test vessel containing 100 mg/L aniline + 30 mg/L sludge, 1 replicate
d) Control: test vessel containing 30 mg/L sludge.
CONTROL AND BLANK SYSTEM
Control blank: test vessel containing basal culture medium (30 mg/L) without test substance or aniline.
INOCULATION OF ACTIVATED SLUDGE:
The activated sludge cultivated was added to each test vessel that the concentration of suspended solid reached to 30 mg/L
ANALYSIS OF TEST SOLUTION:
After the termination of cultivation, total organic carbon and the test substance in the test solutions were determined. The pH of the test solutions were measured. - Reference substance:
- aniline
- Remarks:
- guaranteed reagent, Showa Chemicals Inc.
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 83.4
- Sampling time:
- 14 d
- Results with reference substance:
- Degradability of aniline on Day 7 = 72.4%
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item is considered readily biodegradable.
- Executive summary:
In the current study the ready biodegradability of the test item is assessed similar to OECD 301 C and EU C.4. The oxygen consumption was followed up and additionally DOC removal was determined. No detailed information is available on the results.
The percentage of biodegradation of the test item is 83.4% after 14 days was observed in vessels containing 100 mg/L g test item.
The results indicate that the test item is readily biodegradable according to OECD criteria.
Reference
Description of key information
83.4 % after 14 days (OECD 301C).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One study is available in which the ready biodegradability of the test item is assessed similar to OECD 301 C.
The oxygen consumption was determined.
The percentage of biodegradation was 83.4% after 14 days.
The results indicate that the test item is readily biodegradable.
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