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EC number: 218-524-5 | CAS number: 2172-33-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Vat Orange 011 is considered to be non-toxic to fish, Daphnia magna and microorganisms.
Additional information
The physico-chemical tests with the test substance demonstrated a very poor water solubility of the test substance with an overall solubility of less than1 µg/L. From a regulatory point of view tests on toxicity to the aquatic environment do not need to be performed. Nevertheless, toxicity tests with fish, Daphnia and microorganisms have been performed in the past.
A study performed in 1984 to determine the acute toxicity of FAT 46014 in fish following guideline similar to OECD test guideline 203, reported an LC50 >1000 mg/L.
In the study conducted according to EU Method C.2, exposure of Daphnia magna to the test item FAT 46014/G gave EC50 and EC100 value of greater than 17.1 mg/L (highest tested concentration) at 48h. The No Observed Effect Concentration was 17.1 mg/L at 48 h of exposure.
In accordance with Column 2 of Annex VII of the REACH Regulation, the toxicity testing with aquatic algae does not need to be conducted if the substance is highly insoluble in water. The solubility of FAT 46014/I was found to be below <1 µg/L. An OECD and GLP study was planned to assess the toxicity effect of FAT 46014/I on the aquatic algae. However, the substance was difficult to get into solution even at 1 µg/L under testing conditions. Hence, based on the poor solubility of the substance, testing was considered to be not feasible.
In the study conducted to determine the toxicity of FAT 46014/G to activated sludge in a 3-hour respiration inhibition test according to the OECD Guideline No. 209, the IC50 (3 h) was found to be greater than 320.0 mg/L.
Based on the above discussion, FAT 46014 is considered to be non-toxic to fish, Daphnia magna and microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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