Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
9-bromo-3-(2-bromoacetyl)-8,9,10,11-tetrahydro-5H-6-oxatetraphen-8-one
EC Number:
807-426-3
Cas Number:
1438383-89-1
Molecular formula:
C19H14Br2O3
IUPAC Name:
9-bromo-3-(2-bromoacetyl)-8,9,10,11-tetrahydro-5H-6-oxatetraphen-8-one

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
semiocclusive
Vehicle:
other: aqua ad injectionem
Amount / concentration applied:
0.5 g per test site
Duration of treatment / exposure:
4 hours
Number of animals:
3

Results and discussion

Any other information on results incl. tables

The single dermal application of the test item showed neither irritant nor corrosive effects.

Neither mortalities nor significant clinical signs of toxicity were observed.

Applicant's summary and conclusion

Interpretation of results:
not irritating
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

The test item has obligatory labelling requirement for skin irritation.