Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 215-687-4 | CAS number: 1344-09-8
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- other: General considerations
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Only secondary literature (review).
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Schleyer WL and Blumberg JG (1982). Health, safety and|environmental aspects of soluble silicates. In Soluble|Silicates, Falcone JS (ed). ACS Symposium Series 194,|Chapter 4, 49-69.
- Title:
- No information
- Author:
- Select Committee on GRAS Substances, Evaluation of the Health Aspects of Certain Silicates as Food Ingredients, SCOGS-61, Federation of American Societies for Experimental Biology, NTIS Publication 301-402/AS, Springfield, Va., p.4, 1979.
Materials and methods
- Type of study / information:
- Type of experience: other
- Principles of method if other than guideline:
- General scientific considerations.
Test material
- Reference substance name:
- Silicic acid, sodium salt
- EC Number:
- 215-687-4
- EC Name:
- Silicic acid, sodium salt
- Cas Number:
- 1344-09-8
- Molecular formula:
- Na2O x (SiO2)n with Molar Ratio (MR) (SiO2/Na2O): 1.5 – 4
- IUPAC Name:
- sodium hydroxy(oxo)silanolate
- Details on test material:
- TS-Freetext:
Sodium silicate, no further information on molar ratio and
concentration given.
Constituent 1
Results and discussion
Any other information on results incl. tables
RM-Freetext:
In man, the lethal oral dose of sodium silicates has been
estimated as 0.5-5 g/kg, depending on the molar ratio.
In the USA sodium silicate is considered "generally
recognized as safe (GRAS)" for indirect food uses, and as
additive to drinking water in concentrations of up to 100
ppm.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
