Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
other: Litterature
Adequacy of study:
other information
Study period:
No data
Rationale for reliability incl. deficiencies:
other: Few data are available.
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
publication
Title:
Unnamed

Materials and methods

Study type:
case report
Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
other: Graul und Kalkhoff
Principles of method if other than guideline:
Not detailed
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Hexamethylenediamine
EC Number:
204-679-6
EC Name:
Hexamethylenediamine
Cas Number:
124-09-4
Molecular formula:
C6H16N2
IUPAC Name:
hexane-1,6-diamine
Details on test material:
No data

Method

Type of population:
general
Ethical approval:
other:
Subjects:
No data
Clinical history:
No data
Controls:
No data
Route of administration:
dermal
Details on study design:
No data

Results and discussion

Any other information on results incl. tables

No data

Applicant's summary and conclusion

Conclusions:
Unconclusive.
Executive summary:

The sensibilisation potential of several substances was assessed using the Graul und Kalkhoff methof, following a dermal irritation test. No data are provided about the test conditions. Hexamethylenediamine was irritant. Hexamethylendiamine showed no sensitizing properties on human skin. Few data are available, therefore no conclusion can be made