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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
key study
Study period:
2015
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6

Data source

Reference
Reference Type:
other: software
Title:
Unnamed
Year:
2012
Report date:
2014

Materials and methods

Principles of method if other than guideline:
TEST is a general model for acute toxicity of organic substances. TEST will enable users to easily estimate acute toxicity using QSAR methodologies.
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
bis[2-(2-butoxyethoxy)ethyl] succinate
EC Number:
807-645-4
Cas Number:
701920-77-6
Molecular formula:
C20H38O8
IUPAC Name:
bis[2-(2-butoxyethoxy)ethyl] succinate
Constituent 2
Reference substance name:
bis(2-(2-butoxyethoxy)ethyl)butanedioate
IUPAC Name:
bis(2-(2-butoxyethoxy)ethyl)butanedioate

Test animals

Species:
other: QSAR

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
5 838 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information
Conclusions:
The estimated acute toxicity for the substance bis(2 -(2- butoxyethoxy)ethyl) butanedionate ( LC50 value ) for Rat is .5838 mg/l.
Executive summary:

The acute toxicity was estimated using the TEST model v 4.10 included in the models of US-EPA. . The estimated acute toxicity for the substance bis(2 -(2- butoxyethoxy)ethyl) butanedionate ( LC50 value )for Rat is .5838 mg/l.