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EC number: 212-305-8 | CAS number: 780-69-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- fish early-life stage toxicity
- Data waiving:
- exposure considerations
- Justification for data waiving:
- other:
Reference
Description of key information
A long-term toxicity study on fish is not necessary as:
- exposure considerations in accordance with Annex XI, Section 3, indicate that exposure of aquatic organisms to triethoxy(phenyl)silane (CAS No. 780-69-8) is absent or not significant
and
- the substance has a moderate hazard potential based on the available toxicity data.
Key value for chemical safety assessment
Additional information
In accordance with Annex XI, Section 3, exposure of aquatic organisms to triethoxy(phenyl)silane (CAS 780-69-8), is absent or not significant.
The environmental hazard assessment, PNEC derivation and risk characterization is based on the silanol hydrolysis product, phenylsilanetriol, as the substance hydrolyses rapidly (DT50 = 1.5 h at 20-25 °C and pH 7, QSAR). The other hydrolysis product, ethanol, is known for its absence of environmental toxicity (OECD SIDS, 2004) and thus can be disregarded in the environmental hazard assessment.
Aquatic toxicity data on the parent compound is only available for aquatic invertebrates, for the other two trophic level (fish and algae) good quality data was read-across from a structural analogue substance trichlorophenylsilane (CAS 98-13-5). The source substance hydrolyses rapidly under environmental conditions (DT50 < 1 min at 25°C and pH 4, 7 and 9) to form the structural similar hydrolysis product phenylsilanetriol and hydrogen chloride. The second hydrolysis product, hydrogen chloride, readily dissociates in water into hydrated protons and chloride anions. Thus, it is ionised and neutralisation depends on the buffer capacity of the receiving water. Toxicity only occurs when the buffering capacity of the receiving water is exceeded and pH values fall below pH 6. The pH in rivers and lakes fluctuates within a natural range. The natural pH range in aquatic systems is generally not expected to be perturbed to a relevant extent by anthropogenic emissions when appropriate risk control measures are in place. Variations in effect values of experimental studies can largely be explained by variations in the buffer capacity of the test media (OECD SIDS, 2002). Thus, hydrochloric acid is not expected to have a significant impact on the overall aquatic toxicity of the source compound.
The hazard assessment showed only moderate short-term effects in aquatic invertebrates (daphnia) with an EC50 (48h) = 37 mg/L. No acute effects were observed in fish an algae (EC/LC50 values > 100 mg/L). Consequently, the 48-h EC50 of 37 mg/L obtained in the study on aquatic invertebrates was used for the PNEC derivation as outlined in chapter 6. The silanol hydrolysis product of the registered compound is very well water-soluble. Significant deviations from this overall ecotoxicity profile are not expected and greater long-term toxicity in fish is considered unlikely.
The risk characterization for the silanol hydrolysis product indicated no risk to the aquatic environment (RCR < 1). For detailed information on the risk assessment please refer to the attached documentation in Section 13.
References:
OECD SIDS, 2004. Ethanol - SIDS Initial Assessment Report For SIAM 19, Berlin, Germany: UNEP Publications.
OECD, 2002. Hydrogen Chloride - SIDS Initial Assessment Report for SIAM 15, Boston, USA: UNEP Publications.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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