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Diss Factsheets
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EC number: 912-631-7 | CAS number: 12022-95-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
Ferrosilicon has not been tested for sensitising properties. Lack of skin-sensitising properties of ferrosilicon is supported by the lack of case reports from the ferrosilicon/silicon industry regardless of nearly 100 years of exposure of workers.
Synthetic amorphous silica has not been tested for skin sensitisation, but long and wide-spread use of synthetic amorphous silica without any cases of sensitisation supports the lack of sensitising properties.
The silicon ion is ubiquitous in the environment and amorphous silica is used also as a food additive. Long and wide-spread use of different silicon compounds including silicates and synthetic amorphous silica (e.g., in cosmetics) without any single cases of silica sensitisation supports the lack of sensitising properties in silicon ion. Iron is not a sensitiser, either, and it is sparingly released from the ferrosilicon matrix (release resembling the release of iron from synthetic amorphous silica). Other relevant constituents (strontium and barium) have not been tested for skin sensitisation but have not been reported to exert skin-sensitising properties in humans. The release of other elements from ferrosilicon is low and according to in vitro, data resembles the release from synthetic amorphous silica.
Migrated from Short description of key information:
Long term experience with the use of ferrosilicon has shown no cases of sensitisation. In addition, there is low dissolution of metallic components from the ferrosilicon matrix.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
No cases of respiratory tract sensitisation caused by ferrosilicon, elemental silicon or amorphous silicon dioxide or any other main constituents of ferrosilicon have been reported in the literature.
Migrated from Short description of key information:
No human cases of respiratory sensitisation have been reported.
Justification for classification or non-classification
Ferrosilicon has not been tested for sensitisation. Lack of skin sensitising properties of ferrosilicon is supported by the lack of case reports from the ferrosilicon/silicon industry regardless of nearly 100 years of exposure of workers. Neither has synthetic amorphous silica been tested for skin sensitisation, but long and wide-spread use of synthetic amorphous silica without any cases of sensitisation supports the lack of sensitising properties. The silicon ion is ubiquitous in the environment, and amorphous silica is used also as a food additive. Long and wide-spread use of different silicon compounds, including silicates and synthetic amorphous silica (e.g., in cosmetics) without a single case of silica sensitisation supports the lack of sensitising properties in the silicon ion. Iron is not a sensitiser, and is sparingly released from ferrosilicon matrix (release resembling the release of iron from synthetic amorphous silica). Other relevant constituents released from ferrosilicon matrix include strontium and barium, which have not been tested for skin sensitisation but have not been shown to exert skin-sensitising properties in humans. In addition, their overall dissolution levels from the matrix is very low. The release of other elements from ferrosilicon is low, and according to in vitro data, resembles the release from synthetic amorphous silica. Lack of human cases of respiratory tract sensitisation caused by ferrosilicon supports the lack of respiratory sensitising properties of ferrosilicon.
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