Registration Dossier
Registration Dossier
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EC number: 919-164-8 | CAS number: -
Endpoint summary
Administrative data
Description of key information
There is data available for this substance, which is presented in the dossier.
There was no key experimental data available for this substance or structural analogues for long-term toxicity to fish, short-term toxicity to aquatic invertebrates, long-term toxicity to aquatic invertebrates and toxicity to microorganisms. For these endpoints, the aquatic toxicity was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
The substances are poorly soluble and made of constituents with various water solubility. As a consequence, the exposures were performed with Water Accommodated Fractions (WAFs). Therefore, the results are based on nominal loadings.
According to the harmonised CLP legislation (2008), Annex VI, this substance is classified for the environment as aquatic chronic category 3 with the hazard statement H412: Harmful to aquatic life with long lasting effects.
Additional information
Key and supporting information is summarised below:
Short-term toxicity to fish
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) presented a 96-h LL50 (mortality) range for Oncorhynchus mykiss of 10 -100 mg/L (based on water accomodated fractions).
Long-term toxicity to fish
The long-term aquatic toxicity to fish was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
Short-term toxicity to aquatic invertebrates
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) presented a 48-h LC50 (mortality) range for Daphnia magna of 100 -220 mg/L (based on water accommodated fractions).
Long-term toxicity to aquatic invertebrates
The long-term toxicity to aquatic invertebrates was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
Toxicity to algae and cyanobacteria
Hydrocarbons, C10-C13, n-alkanes, isoalkanes, cyclics, aromatics (2-25%) presented 72-hour EbL50 (biomass) and ErL50 (growth rate) values within the range if 10-100 mg/L for Raphidocelis subcapitata. The 72-hr NOEL values for biomass and growth rate were 3 mg/L, respectively. (Based on water accommodated fractions).
Toxicity to microorganisms
The toxicity to microorganisms was estimated using the PETROTOX computer model (v4.0), which combines a partitioning model used to calculate the aqueous concentration of hydrocarbon components as a function of substance loading with the Target Lipid Model used to calculate acute and chronic toxicity of nonpolar narcotic chemicals. PETROTOX computes toxicity based on the summation of the aqueous-phase concentrations of hydrocarbon block(s) that represent a hydrocarbon substance and membrane-water partitioning coefficients (KMW) that describe the partitioning of the hydrocarbons between the water and organism.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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