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Diss Factsheets
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EC number: 201-286-1 | CAS number: 80-51-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_ecotoxicological-information.png)
Endpoint summary
Administrative data
Description of key information
The following ecotoxicity data for aquatic organisms is available for OBSH (m = measured concentration). It should be noted that these values may reflect toxic effects of degradation products as well as the parent compound.
Short-term toxicity
Fish [Oryzias latipes]: LC50(96 hrs) > 6.6 mg/L (m, semi-static)
Invertebrates [Daphnia magna]: EC50(48 hrs) = 2.9 mg/L (m, semi-static)
Algae [Pseudokirchneriella subcapitata]: EC50(72 hrs) = 0.35 mg/L (growth rate) (m, static)
Long-term toxicity:
NOEC for freshwater fish (Oryzias latipes, Early-Life Stage Toxicity Test, 45d): 0.09 mg/L (m, flow-through)
NOEC for freshwater invertebrates (Daphnia magna, 21 d reproduction study): 2.13 mg/L (m, semi-static)
NOEC for fresh water algae (Pseudokirchnerella subcapitata, 3 d, growth rate): 0.059 mg/L (m, static)
Additional information
Furthermore, the hydrolysis studies showed quite short hydrolysis half-lives of 5.9 hr (pH=9), 7.9 (pH=7), 11.7 (pH=4). The pH range of the toxicity studies were in the range of 7.3 – 9.0. At these pH-ranges, a large percentage of the mother substance is degraded (>65% after 12 hours, >88% after 24 hours, >98% after 48 hours) during the test, if no water exchange has been carried out. The main degradation products from the hydrolysis have been identified to be hydrazine (CAS No. 302-01-2) and 4,4’-oxybis(benzenesulfonic acid) (SIDS Initial Assessment Profile,http://webnet.oecd.org/hpv/ui/handler.axd?id=f4e8a387-2cf6-49f6-8af6-78ea04bf97a3). It is very likely that especially hydrazine has contributed to the observed toxicity.
Therefore, the environmental safety assessment must be performed for OBSH degradation products. Hydrazine monohydrate was used as a worst-case scenario, because it is very toxic to environmental organisms and is classified as hazardous to the aquatic environment H400, Acute Hazard, Category 1 and H 410, Chronic Hazard, Category 1 according to the CLP Regulation.
No literature toxicity data can be found for the other main degradation product, namely 4,4’-oxybis(benzenesulfonic acid, but data for similar substances such as Disodium oxybis(methylbenzenesulfonate, 4-hydroxybenzenesulphonic acid, Benzene sulfonic acids and Hydropes were less toxic compared to hydrazine monohydrate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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